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Journal / Bioengineering / Automatisering af mikronukleusanalysen ved hjælp…
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Bioengineering

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JoVE Journal Bioengineering
Automatisering af mikronukleusanalysen ved hjælp af billeddannelsesflowcytometri og kunstig intelligens
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Automatisering af mikronukleusanalysen ved hjælp af billeddannelsesflowcytometri og kunstig intelligens

Article DOI: 10.3791/64549-v • 09:11 min • January 27th, 2023
January 27th, 2023 •
1, 1, 1, 1, 1, 1, 1, 1, 1, 1
1Amnis Flow Cytometry, Luminex Corporation

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Mikronukleusanalysen (MN) er en veletableret test til kvantificering af DNA-skader. Imidlertid er det besværligt og udfordrende at score analysen ved hjælp af konventionelle teknikker såsom manuel mikroskopi eller funktionsbaseret billedanalyse. Dette papir beskriver metoden til at udvikle en kunstig intelligensmodel til at score MN-analysen ved hjælp af billeddannelsesflowcytometridata.

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Bioengineering udgave 191 mikronukleusanalyse genotoksicitet cytotoksicitet billeddannelsesflowcytometri billedanalyse maskinindlæring kunstig intelligens
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