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Journal / Medicine / Partielle Ischiasnervligatur: Ein Mausmodell für…
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Partielle Ischiasnervligatur
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Partielle Ischiasnervligatur: Ein Mausmodell für chronische neuropathische Schmerzen zur Untersuchung der antinozizeptiven Wirkung neuartiger Therapien

Article DOI: 10.3791/64555-v • 08:16 min • October 6th, 2022
October 6th, 2022 •
1, 1, 2, 1, 1, 5, *1,2,3,4, *1,2
1Department of Pharmacology, College of Medicine, The University of Arizona, Tucson, 2Department of Anesthesiology, College of Medicine, The University of Arizona, Tucson, 3Neuroscience Graduate Interdisciplinary Program, College of Medicine, The University of Arizona, Tucson, 4Comprehensive Pain and Addiction Center, The University of Arizona, Tucson, 5Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center
* These authors contributed equally

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Die partielle Ligatur des Ischiasnervs induziert lang anhaltende chronische neuropathische Schmerzen, die durch übertriebene Reaktionen auf thermische und mechanische Reize gekennzeichnet sind. Dieses Mausmodell für neuropathische Schmerzen wird häufig verwendet, um innovative Therapien zur Schmerzbehandlung zu untersuchen. Dieser Artikel beschreibt detailliert das chirurgische Verfahren zur Verbesserung der Standardisierung und Reproduzierbarkeit.

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Medizin Heft 188
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