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Immunology and Infection

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JoVE Journal Immunology and Infection
Differentiering af funktionelle osteoklaster fra humant perifert blod CD14+ monocytter
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Differentiering af funktionelle osteoklaster fra humant perifert blod CD14+ monocytter

Article DOI: 10.3791/64698-v • 11:52 min • January 27th, 2023
January 27th, 2023 •
*1, *1, 1, 1
1School of Infection & Immunity, University of Glasgow
* These authors contributed equally

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Osteoklaster er vigtige knogleresorberende celler i kroppen. Denne protokol beskriver en pålidelig metode til in vitro-differentiering af osteoklaster fra humane perifere blodmonocytter. Denne metode kan bruges som et vigtigt redskab til yderligere at forstå osteoklastbiologi i homeostase og i sygdomme.

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Immunologi og infektion udgave 191 Monocytter osteoklaster resorption osteoklastogenese
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