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Isolamento e cultura de células-tronco derivadas de tecido adiposo humano com um método inovador livre de xenogênicos para terapia humana
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Isolamento e cultura de células-tronco derivadas de tecido adiposo humano com um método inovador livre de xenogênicos para terapia humana

Article DOI: 10.3791/65104-v • 06:00 min • February 3rd, 2023
February 3rd, 2023 •
*1,4, *2, 2, 3, 4, 4, 1, 1
1Department of Plastic, Reconstructive and Hand Surgery, Centre Hospitalier Universitaire Vaudois (CHUV, 2Cell and Tissue Engineering Lab, IRCCS Ospedale Galeazzi Sant'Ambrogio, 3Unit of Regenerative Therapy, Plastic, Reconstructive and Hand Surgery, Department of Musculoskeletal Medicine, Lausanne University Hospital, 4Centre for the Cellular Microenvironment, University of Glasgow
* These authors contributed equally

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Os produtos xenogênicos (químicos ou derivados de animais) introduzidos nas etapas de preparação/manipulação da terapia celular estão associados a um risco aumentado de reatividade imunológica e transmissão patogênica em pacientes hospedeiros. Aqui, um método completo livre de xenogênicos para o isolamento e expansão in vitro de células-tronco derivadas de tecido adiposo humano é descrito.

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Medicina Edição 192
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