Brain Activation Patterns

Brain activation patterns are the organized changes in neural activity that occur across brain regions during particular behaviors, cognitive tasks, or emotional states. They arise as networks of neurons communicate through electrical and chemical signals, producing coordinated increases or decreases in activity that can be measured with methods such as functional neuroimaging or electrophysiology. In behavioral research, comparing these patterns helps link perception, learning, decision-making, motivation, and motor responses to underlying neural circuits. Studying how activation changes across conditions or individuals can clarify brain-behavior relationships and provide insight into neurological and psychiatric disorders.

Brain Activation Patterns - Related Videos

Research

JoVE Journal - Neuroscience
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Cross-Modal Multivariate Pattern Analysis

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Cited by 5 •

2011

Classical multivariate pattern analysis predicts sensory stimuli a subject perceives from neural activity in the corresponding cortices (e.g. visual stimuli from activity in visual cortex). Here, we apply pattern analysis cross-modally and show that sound- and touch-implying visual stimuli can be predicted from activity in auditory and somatosensory cortices, respectively.

Research

JoVE Journal - Neuroscience

In vivo Positron Emission Tomography to Reveal Activity Patterns Induced by Deep Brain Stimulation in Rats

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2022

We describe a preclinical experimental method to evaluate metabolic neuromodulation induced by acute deep brain stimulation with in vivo FDG-PET. This manuscript includes all experimental steps, from stereotaxic surgery to the application of the stimulation treatment and the acquisition, processing, and analysis of PET images.

Recording Electrical Activity from Identified Neurons in the Intact Brain of Transgenic Fish

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Cited by 4 •

2013

In this video, we will demonstrate how to record electrical activity from identified single neurons in a whole brain preparation, which preserves complex neural circuits. We use transgenic fish in which gonadotropin-releasing hormone (GnRH) neurons are genetically tagged with a fluorescent protein for identification in the intact brain preparation.

Modelling Brain Metastasis: Standardized Analysis of Metastatic Colonization and Histological Growth Patterns by Stereotactic Intracortical Injection

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Cited by 1 •

2026

The stereotactic intracranial injection technique enables precise and localized implantation of tumor cells into the mouse cortex, making it a powerful model for studying metastatic colonization of the brain.

A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity

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Cited by 18 •

2017

This protocol presents a method for creating a large unilateral craniotomy over the temporal and parietal regions of the mouse cerebral cortex. This is especially useful for real time imaging over an expansive area of a cortical hemisphere.

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