Escape Cage

An escape cage is a behavioral testing apparatus that provides an animal with access to a protected enclosure when it encounters an aversive or threatening stimulus. During testing, researchers present the stimulus and measure responses such as escape latency, movement between compartments, time spent in the safe area, and repeated avoidance behavior. These measurements help characterize defensive behavior, threat perception, stress responses, learning, and motivation across species. Escape-cage paradigms can also evaluate how experimental conditions, sensory cues, or neurological changes alter an animal’s ability to recognize danger and select an appropriate escape strategy.

Escape Cage - Related Videos

Research

JoVE Journal - Neuroscience

Optogenetic Stimulation of Escape Behavior in Drosophila melanogaster

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Cited by 24 •

2013

Genetically encoded optogenetic tools enable noninvasive manipulation of specific neurons in the Drosophila brain. Such tools can identify neurons whose activation is sufficient to elicit or suppress particular behaviors. Here we present a method for activating Channelrhodopsin2 that is expressed in targeted neurons in freely walking flies.

Education

JoVE Core - Physics

Escape Velocity

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2025

The escape velocity of an object is defined as the minimum initial velocity that it requires to escape the surface of another object to which it is gravitationally bound and never to return. For example, what would be the minimum velocity at which a satellite should be launched from the Earth's surface such that it just escapes the Earth's gravitational field? To calculate the escape velocity, it is assumed that no energy is lost to any frictional forces. In practice, a satellite launched from...

Generation of Influenza Virus Escape Variants against Neutralizing Antibodies

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2025

This video demonstrates a technique for generating escape variants of neutralizing influenza virus monoclonal antibodies. Antibody-neutralized virus suspension is injected into embryonated chicken eggs to propagate escape variants selectively. This results in a virus population predominantly of escape variants, confirmed via a Hemagglutination assay.

Research

JoVE Journal - Biology
Free Sample

Maintenance of a Drosophila melanogaster Population Cage

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Cited by 8 •

2016

This manuscript reports a detailed protocol for culturing, on a regular basis, a population of Drosophila melanogaster using a fly population cage.

A Treatment Package without Escape Extinction to Address Food Selectivity

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Cited by 9 •

2015

Feeding difficulties are a common problem for children with developmental disorders, including autism, and behavioral interventions often include escape extinction. Recent research has begun to evaluate treatments that do not include escape extinction. This manuscript describes a multicomponent treatment package that does not use escape extinction to treat feeding difficulties.

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