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Optogenetic Stimulation of Escape Behavior in Drosophila melanogaster
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Optogenetic Stimulation of Escape Behavior in Drosophila melanogaster

Article DOI: 10.3791/50192 • 08:03 min • January 25th, 2013
January 25th, 2013 •
1, 1
1Department of Neurobiology, Stanford University

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Genetically encoded optogenetic tools enable noninvasive manipulation of specific neurons in the Drosophila brain. Such tools can identify neurons whose activation is sufficient to elicit or suppress particular behaviors. Here we present a method for activating Channelrhodopsin2 that is expressed in targeted neurons in freely walking flies.

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Optogenetic Stimulation Escape Behavior Drosophila Melanogaster Genetically Encoded Tools Neural Activity Manipulation Optogenetic Tools Channelrhodopsin (ChR2) Depolarization CO2 Avoidance Proboscis Extension Giant-fiber Mediated Startle Response Phototransduction Impairment Loom-sensitive Neurons Fly's Optic Lobe Foma-1 Neurons Collision Avoidance Behavior Null Allele Phospholipase C-beta NorpA Gene Gal4-UAS Transcriptional Activator System Blue LEDs
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