Ciliary Epithelium

Ciliary epithelium is a specialized, double-layered epithelial tissue in the ciliary body of the eye that supports vision by contributing to aqueous humor production and lens accommodation. Its pigmented and nonpigmented cell layers develop from the optic cup and work together through ion transport, fluid movement, and tight junctions; contraction of the ciliary muscle also changes tension on the zonular fibers, altering lens curvature for near focus. Studying this tissue helps explain intraocular pressure, the blood-aqueous barrier, and disorders such as glaucoma, while its cellular organization provides a model for epithelial transport and ocular development.

Ciliary Epithelium - Related Videos

Research

JoVE Journal - Biology

Determining Ciliary Function and Membrane Impermeability of the Pseudostratified Lung Airway Epithelium

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2025

Air-liquid interface culture is commonly used to develop pseudostratified airway epithelium by differentiating primary normal human bronchial epithelial cells that mimic the apical side of the lung airway. Here, we describe an easy protocol for determining its quality by monitoring its biophysical properties, such as ciliary function and membrane integrity.

Isolating Short Posterior Ciliary Arteries: A Protocol to Excise Intact Short Posterior Ciliary Microvessels from Porcine Eye

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2025

This video describes the protocol to isolate the short posterior ciliary arteries from the porcine eye. The isolated short posterior arteries are a suitable source for elucidating the molecular insights and protein profiles of the ocular blood vessels.

Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo

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Cited by 6 •

2015

In this study, a detailed light microscopic technique was optimized for real-time observation and analysis of the motion of CPEC cilia ex vivo together with an electron microscopic method for ultrastructural analysis.

Dissection of a Mouse Eye for a Whole Mount of the Retinal Pigment Epithelium

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Cited by 45 •

2011

A formal demonstration of the dissection of a mouse eye, resulting in a whole mount of the retinal pigment epithelium.

Education

JoVE Core - Anatomy and Physiology

Mechanism of Ciliary Motion

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2023

The ciliary structures were first seen in 1647 by Antonie Leeuwenhoek while observing the protozoans. In lower organisms, these appendages are responsible for cell movement, while in higher organisms, these appendages help in the movement of the extracellular fluids within the body cavities. The cilia are made up of microtubules in a 9+2 arrangement, with nine microtubule doublet ring bundles, surrounding a pair of central singlet microtubule bundles. The doublet microtubule bundles are...

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