Fabry-perot Interferometer

A Fabry–Pérot interferometer is an optical device that measures light through interference produced by two parallel, partially reflecting surfaces. Light repeatedly reflects within the resonant cavity, and only wavelengths satisfying the cavity’s phase-matching condition undergo strong transmission, producing sharp interference peaks. In biology, this principle supports high-resolution spectroscopy and optical measurements of biological samples, including changes in refractive index, molecular composition, and thin-film or tissue properties. Its sensitivity to small wavelength shifts makes it useful for analyzing biomolecules, characterizing optical biosensors, and monitoring biochemical interactions without directly labeling the target.

Fabry-perot Interferometer - Related Videos

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JoVE Journal - Engineering
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Fabrication of a Low-Cost, Fiber-Coupled, and Air-Spaced Fabry-Pérot Etalon

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Cited by 2 •

2023

This protocol describes the construction of a low-cost, discrete, fiber-coupled, and air-spaced Fabry-Perot etalon with various applications, such as in trace-gas spectroscopy. The fabrication is possible in any facility with standard optical laboratory equipment available.

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JoVE Journal - Engineering

Implementation of a Reference Interferometer for Nanodetection

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2014

A reference interferometer technique, which is designed to remove undesirable laser jitter noise for nanodetection, is utilized for probing an ultra-high quality factor microcavity. Instructions for assembly, setup, and data acquisition are provided, alongside the measurement process for specifying the cavity quality factor.

In Vitro Enzyme Measurement to Test Pharmacological Chaperone Responsiveness in Fabry and Pompe Disease

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Cited by 5 •

2017

There is a demand to make pre-clinical testing for a novel class of "orphan" drugs called pharmacological chaperones reproducible, fast, and efficient. We developed a simple, highly standardized, and versatile cell culture-based assay to screen for eligible patients as well as novel pharmacological chaperone drugs.

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JoVE Journal - Engineering
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The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

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Cited by 7 •

2013

Large laser-interferometers are being constructed to create a new type of astronomy based on gravitational waves. Their sensitivities, as for many other high-precision experiments, are approaching fundamental noise limits such as the atomic vibration of their components. We are pioneering technologies to overcome these limits using novel laser beam shapes.

Quantum State Engineering of Light with Continuous-wave Optical Parametric Oscillators

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Cited by 13 •

2014

We describe the reliable generation of non-Gaussian states of traveling optical fields, including single-photon states and coherent state superpositions, using a conditional preparation method operated on the non-classical light emitted by optical parametric oscillators. Type-I and type-II phase-matched oscillators are considered and common procedures, such as the required frequency filtering or the high-efficiency quantum state characterization by homodyning, are detailed.

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