Fecal Oral Route

The fecal-oral route is a pathway of disease transmission in which microorganisms from fecal matter enter another person’s mouth, making it important in biology, epidemiology, and public health. Transmission occurs when contaminated hands, food, water, or surfaces carry pathogens that are then ingested; inadequate sanitation and hygiene can increase this exposure. After ingestion, infectious agents may survive passage through the digestive system, colonize or damage intestinal tissues, and spread through fecal shedding. Understanding this route supports investigation of outbreaks and informs interventions such as handwashing, safe water treatment, food hygiene, sanitation infrastructure, and vaccination programs.

Fecal Oral Route - Related Videos

Education

JoVE Core - Pharmacokinetics and Pharmacodynamics

Non-Oral Extravascular Drug Absorption Routes

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2024

Non-oral extravascular routes, which encompass sublingual, buccal, topical, intramuscular, and inhalation methods, primarily utilize passive diffusion to transport drugs into the systemic circulation. The absorption rates and effectiveness of these routes depend on the drug's physicochemical properties, as well as the patient's anatomical and pathophysiological state. Lipophilic drugs that are stable at salivary pH (6) and exhibit minimal binding to the oral mucosa are absorbed more effectively...

Routes of Persuasion

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2020

Persuasion is the process of changing our attitude toward something based on some kind of communication. Much of the persuasion we experience comes from outside forces. How do people convince others to change their attitudes, beliefs, and behaviors? What communications do you receive that attempt to persuade you to change your attitudes, beliefs, and behaviors? Yale Attitude Change Approach The topic of persuasion has been one of the most extensively researched areas in social psychology...

Research

JoVE EoE - Immunotherapy

Evaluating the Effects of Fecal Microbiota Transplantation in an Interleukin-10 Deficient Mouse

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2025

This video demonstrates a procedure of fecal microbiota transplantation in an interleukin-10 deficient mouse with colon inflammation. Colonized fecal microbes in the gut release secondary metabolites, eliciting anti-inflammatory cytokine release and reducing colon inflammation.

Isolation of Fecal Bacteria from Water Samples by Filtration

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2023

Source: Laboratories of Dr. Ian Pepper and Dr. Charles Gerba - The University of Arizona Demonstrating Author: Luisa Ikner The quality of water destined for use in agricultural, recreational, and domestic settings is of great importance due to the potential for outbreaks of waterborne disease. Microbial agents implicated in such events include parasites, bacteria, and viruses that are shed in high numbers in the feces of infected people and animals. Transmission to new and susceptible hosts may...

Oral Infection Alters the Gut Microbiota in a Rat Model

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2026

Begin with a rat model with sutures tied around its upper molar teeth to support bacterial colonization.Repeatedly smear the sutures with a gum disease-causing oral pathogenic bacterium using a gel-like solution.The bacteria colonize the gum around the sutures.Colonization triggers inflammation and damages the tissues.The bacteria release toxins that diffuse through damaged tissues and enter the bloodstream.These circulating toxins reach the gut, cause inflammation, disrupt the epithelial...

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