Fluoride Hydroxyapatite
Fluoride Hydroxyapatite - Related Videos
05:41
Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
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Cited by 18 •
2017
This paper describes a novel method for the rapid manufacture of high quality bioinspired nanoscale hydroxyapatite. This biomaterial is of great significance in the manufacture of a wide range of innovative medical devices for clinical applications in orthopedics, craniofacial surgery and dentistry.
13:46
Separation of Single-stranded DNA, Double-stranded DNA and RNA from an Environmental Viral Community Using Hydroxyapatite Chromatography
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Cited by 5 •
2011
We describe an efficient method to separate single-stranded DNA, double-stranded DNA and RNA molecules from environmental viral communities. Nucleic acids are fractionated using hydroxyapatite chromatography with increasing concentrations of phosphate-containing buffers. This method permits the isolation of all viral nucleic acid types from environmental samples.
07:14
Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
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Cited by 4 •
2022
Novel nanocomposites of graphene nanoribbons and hydroxyapatite nanoparticles were prepared using solution-phase synthesis. These hybrids when employed in bioactive scaffolds can exhibit potential applications in tissue engineering and bone regeneration.
09:57
18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor (SiFA) for Positron Emission Tomography
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Cited by 3 •
2020
The synthesis of fluorine-18 (18F) labeled radiopharmaceuticals for positron emission tomography typically requires months of experience. When incorporated into a radiotracer, the silicon-fluoride acceptor (SiFA) motif enables a simple 18F-labeling protocol that is independent of costly equipment and preparatory training, while reducing precursor quantity needed and utilizing milder reaction conditions.
14:20
High Throughput SiRNA Screening for Chloropicrin and Hydrogen Fluoride-Induced Cornea Epithelial Cell Injury
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Cited by 8 •
2018
High throughput small inhibitory RNA screening is an important tool that could help to more rapidly elucidate the molecular mechanisms of chemical cornea epithelial injury. Herein, we present the development and validation of exposure models and methods for the high throughput screening of hydrogen fluoride- and chloropicrin-induced cornea epithelial injury.
FAQs
Fluoride substitution changes the hydroxyapatite crystal lattice, making the mineral less soluble when exposed to acid. This matters because bacterial acid production can drive enamel mineral loss. By resisting dissolution more effectively, the fluoride-containing mineral helps preserve enamel structure during acidic episodes and contributes to the protective basis of fluoride in dental disease prevention.
Replacing some hydroxyl ions with fluoride produces a more stable crystal arrangement than ordinary hydroxyapatite. The resulting lattice is less readily dissolved under acidic conditions, so mineralized tissues can retain their inorganic structure more effectively. This crystal-level change explains why fluoride hydroxyapatite is important in studying both enamel durability and mineral stability.
When fluoride is available, it supports the formation or stabilization of fluoride-containing mineral during enamel repair. This process can help replace mineral lost during acid exposure and increase resistance to subsequent dissolution. The outcome depends on fluoride being present where mineralized tissue is undergoing change, linking fluoride availability with remineralization and prevention of mineral loss.
Dental researchers use fluoride hydroxyapatite as a mineral model for examining how preventive treatments affect enamel stability and mineral loss. Studies can focus on whether treatment-related fluoride promotes a less soluble mineral phase or supports remineralization after acidic challenge. These observations help connect a treatment’s mineral-level effects with its potential to protect enamel.
Its stable, acid-resistant mineral characteristics provide a model for designing materials that imitate aspects of natural enamel. Biomimetic research can use this mineral as a reference when developing approaches intended to restore or reinforce damaged enamel. The goal is to reproduce useful features of mineralized tissue rather than treating repair as a purely organic process.
The mineral is investigated in biomimetic materials for bone substitutes as well as enamel repair. Its connection to the inorganic phase of mineralized tissues makes it useful for studying how synthetic materials may interact with or resemble biological mineral. These applications extend the relevance of fluoride hydroxyapatite from dental protection to broader biomedical material development.