Genetic Engineering
Genetic Engineering - Related Videos
10:38
An Overview of Genetic Engineering
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2023
Genetic engineering – the process of purposefully altering an organism’s DNA – has been used to create powerful research tools and model organisms, and has also seen many agricultural applications. However, in order to engineer traits to tackle complex agricultural problems such as stress tolerance, or to realize the promise of gene therapy for treating human diseases, further advances in the field are still needed. Important considerations include the safe and efficient delivery of genetic...
09:36
Genetic Engineering of Model Organisms
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2023
Transgenesis, or the use of genetic engineering to alter gene expression, is widely used in the field of developmental biology. Scientists use a number of approaches to alter the function of genes to understand their roles in developmental processes. This includes replacement of a gene with a nonfunctional copy, or adding a visualizable tag to a gene that allows the resultant fusion protein to be tracked throughout development. In this video, the viewers will learn about the principles behind...
01:34
What is Genetic Engineering?
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2026
Genetic engineering is the process of modifying an organism’s DNA to introduce new, desirable traits. Many organisms, from bacteria to plants and animals, have been genetically modified for academic, medical, agricultural, and industrial purposes. While genetic engineering has definite benefits, ethical concerns surround modifying humans and our food supply.Scientists can Deliberately Modify an Organism’s GenomeGenetic engineering is possible because the genetic code—the way information is...
05:01
Agrobacterium-Mediated Genetic Transformation: A Method to Genetically Transform the Rice Genome via Genetically Engineered Agrobacterium tumefaciens
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2025
In this video, we demonstrate genetic transformation of the rice genome using an Agrobacterium tumefaciens binary vector. This bacterium facilitates the transfer of a foreign DNA plasmid using Agrobacterium virulence proteins.
10:10
Genetic Engineering of an Unconventional Yeast for Renewable Biofuel and Biochemical Production
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Cited by 20 •
2016
We herein report methods on the molecular genetic manipulation of the Yarrowia lipolytica Po1g strain for improved gene deletion efficiency. The resulting engineered Y. lipolytica strains have potential applications in biofuel and biochemical production.
FAQs
Both approaches enable researchers to change genetic material, but they are described in the overview as distinct tools. Recombinant DNA technology supports the deliberate construction or introduction of selected DNA sequences, while CRISPR-based genome editing can target defined regions of a genome. Choosing between them depends on whether the research requires sequence insertion, removal, alteration, or targeted genome modification.
Targeting a defined genomic region connects a planned DNA change with a specific location in the genome. This makes it possible to investigate how that region relates to gene expression, protein production, or a biological trait. In biology, such targeted changes help researchers link a particular genetic sequence with the function or process it influences.
A DNA change can modify how genetic information affects gene expression or protein production. Because proteins contribute to biological processes, altered production can lead to a measurable change in an organism or cell. Researchers use this relationship to connect a deliberate genetic modification with an observable trait and to study the molecular basis of biological functions.
A typical investigation begins by identifying a DNA sequence connected to the biological question, then selecting whether to insert, remove, or alter that sequence. Researchers next examine effects on gene expression, protein production, or an observable trait. This sequence of steps turns a planned genetic change into evidence about gene function or a useful biological outcome.
Applications span medicines, engineered microorganisms, improved crops, and experimental models of disease. The same underlying ability to modify genetic material can therefore serve production goals as well as biological research. In practice, researchers may focus on changing a useful trait, producing a desired protein, or creating a model that reveals how a disease-related process operates.
Researchers can change a selected DNA sequence and then relate that modification to changes in gene expression, protein production, or observable traits. This comparison provides a way to test how genetic material contributes to a biological process rather than only describing the sequence itself. The approach is especially valuable for examining molecular mechanisms and developing experimental disease models.