Gradualism

Gradualism is the scientific concept that change occurs through a series of small, continuous steps rather than sudden transformations, and in biology it describes one pattern of evolutionary change. In evolutionary gradualism, heritable variation is filtered by natural selection over successive generations, allowing populations to accumulate incremental differences in traits, behavior, or physiology. This framework helps explain how new adaptations and species can arise over long timescales and guides interpretation of fossil sequences, comparative anatomy, and genetic evidence. Comparing gradual change with punctuated patterns also helps researchers evaluate the tempo and mechanisms of evolution across different environments and lineages.

Gradualism - Related Videos

Education

JoVE Core - Civil Engineering

Gradually Varying Flow

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2025

Gradually varying flow (GVF) in open channels describes situations where water depth changes slowly along the channel due to factors like non-uniform bed slope, channel shape variations, or obstructions. This flow type occurs when the depth adjusts gradually to balance gravitational forces, shear forces, and energy requirements, resulting in a low rate of depth change.Characteristics of Gradually Varying FlowGVF is commonly observed in natural streams, rivers, and canals, where flow depth...

Research

JoVE Journal - Bioengineering

Monitoring the Wall Mechanics During Stent Deployment in a Vessel

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2012

Stent-induced arterial strain distributions are characterized using an optical surface strain measurement system. This visualization technique is used to gain insights into the impact of stent implantation on the host vessel.

Transduction of a Humanized Rat Liver Using Adeno-associated Virus Vectors

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2026

Source: Hiller, T., et al. Study of Viral Vectors in a Three-dimensional Liver Model Repopulated with the Human Hepatocellular Carcinoma Cell Line HepG2. J. Vis. Exp., (2016)This video demonstrates adeno-associated virus-mediated gene delivery in a humanized rat liver scaffold. The vector delivers a transgene encoding a fluorescent reporter and gene-silencing RNA into liver cells via receptor-mediated endocytosis. This model supports efficient transduction in a perfused 3D liver tissue system.

Recording of Mesenteric Afferent Nerve Activity in an Ex Vivo Mouse Jejunum Segment

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2025

This video shows the process of recording electrical signals from mesenteric afferent nerves in a dissected mouse jejunal segment to study the effects of tissue pressure and movement changes on afferent nerve activity.

Dissection of the Eye-Brain Complex from Fly Pupae: A Method to Isolate Retinal Tissue

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2023

This video describes how to dissect and isolate the eye-brain complex from Drosophila pupae. The featured protocol demonstrates the procedure yielding high-quality tissue, compatible with, for example, immunostaining, as well as, other gene expression experiments.

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