Microencapsulation
Microencapsulation - Related Videos
10:54
Extraction of Plant-based Capsules for Microencapsulation Applications
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Cited by 5 •
2016
This protocol/manuscript describes a streamlined process for the production of sporopollenin exine capsules (SECs) from Lycopodium clavatum spores and for the loading of hydrophilic compounds into these SECs.
09:39
Constructing a Collagen Hydrogel for the Delivery of Stem Cell-loaded Chitosan Microspheres
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Cited by 6 •
2012
A major hurdle in current stem cell therapies is determining the most effective method to deliver these cells to host tissues. Here, we describe a chitosan-based delivery method that is efficient and simple in approach, while allowing adipose-derived stem cells to maintain their multipotency.
11:19
An Introduction to Stem Cell Biology
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2023
Cells that can differentiate into a variety of cell types, known as stem cells, are at the center of one of the most exciting fields of science today. Stem cell biologists are working to understand the basic mechanisms that regulate how these cells function. These researchers are also interested in harnessing the remarkable potential of stem cells to treat human diseases. Here, JoVE presents an introduction to the captivating world of stem cell biology. We begin with a timeline of landmark...
11:13
Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules
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Cited by 3 •
2015
Scaffolds for tissue engineering need to recapitulate the complex biochemical and biophysical microenvironment of the cellular niche. Here, we show the use of interfacial polyelectrolyte complexation fibers as a platform to create composite, multi-component polymeric scaffolds with sustained biochemical release.
FAQs
Release depends on how readily the enclosed material moves through the coating and whether the shell breaks down. Diffusion can regulate exposure over time, while shell degradation can alter the barrier surrounding the core. Environmental conditions also influence these processes, making release behavior relevant when researchers want to control contact between a biological material and its surroundings.
Polymers and lipids form the protective shell around the enclosed material. Their presence can reduce exposure to moisture, oxygen, enzymes, or incompatible surroundings, helping sensitive biological compounds remain stable. Because the shell also participates in diffusion and degradation, its composition contributes both to protection during handling and to how the core becomes available later.
Moisture, oxygen, enzymes, and other incompatible surroundings can affect how well the shell protects its core. Environmental conditions may also change diffusion or shell degradation, thereby influencing release. These factors matter in biology because the same coating can support stability during storage or handling while still permitting controlled interaction with the surrounding environment.
Preparation begins with placing a small amount of solid, liquid, or biological material inside a protective coating. Researchers can form the particles through emulsification, coacervation, or spray drying, using a polymer or lipid shell. The resulting particles are then considered in terms of protection, handling, stability, and the conditions governing release.
Researchers may choose this approach when a biological material needs protection, improved handling, greater stability, or controlled exposure. Relevant uses include drug delivery, probiotic stabilization, enzyme stabilization, and cell-based research. The technique is especially useful when investigators need to manage how a compound or biological agent interacts with moisture, oxygen, enzymes, or its surroundings.
Microencapsulation can help researchers examine whether a biological material remains protected and stable, how easily it can be handled, and when it becomes exposed. By observing release in relation to diffusion, shell degradation, and environmental conditions, investigators can study controlled delivery or explore how biological agents interact with their environment.