Neuro Plex

Neuro plex describes an interconnected network of neurons and nerve fibers that organizes communication within the nervous system, making it possible to coordinate sensory input, processing, and physiological responses. Signals move through branching axons and synaptic connections, where electrical impulses trigger chemical neurotransmitter release and are integrated by downstream cells. In biology, studying these networks helps clarify how neural circuits regulate movement, sensation, and autonomic functions, while also supporting research into developmental disorders, nerve injury, and neurological disease. Mapping connectivity and signal flow can guide experiments on circuit function and potential therapeutic strategies.

Neuro Plex - Related Videos

Research

JoVE Journal - Immunology and Infection

High-plex Imaging using Spectral Confocal Microscopy to Minimize Non-specific Tissue Fluorescence

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2025

Spectral Iterative Bleaching Extends Multiplexity (IBEX) builds upon the base IBEX technique by adding heparin blocking to minimize nonspecific binding and leveraging spectral detection with computational unmixing to suppress autofluorescence. This approach accelerates image acquisition while reducing sources of background, enabling robust multi-round, high-parameter spatial proteomic analyses.

Research

JoVE Journal - Behavior
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Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

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Cited by 10 •

2016

This article reports the development of a neuro-rehabilitation approach, "constraint-induced sound therapy (CIST)" for sudden sensorineural hearing loss. The aim of CIST is to prevent maladaptive cortical reorganization by using an enriched acoustic environment. CIST represents a safe, easy, inexpensive, and effective approach to treat sudden sensorineural hearing loss.

Research

JoVE Journal - Neuroscience
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Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

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Cited by 9 •

2015

In this paper, an experimental framework to perform closed-loop experiments is presented, in which information processing (i.e., coding and decoding) and learning of neuronal assemblies are studied during the continuous interaction with a robotic body.

Fluorescence Imaging of Neuro-Immune Dynamics Using a Skull Implant

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2025

Source: Bisht, K., et al. Precise brain mapping to perform repetitive in vivo imaging of neuro-immune dynamics in mice. J. Vis. Exp. (2020)This video demonstrates fluorescence imaging of neuro-immune dynamics in a transgenic mouse with a skull implant. Vascular and neuronal stability is imaged alongside dynamic microglial changes, reflecting immune responses to neuronal activity.

High Resolution 3D Imaging of the Human Pancreas Neuro-insular Network

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Cited by 21 •

2018

Here, we present a protocol to image human pancreas sections in three dimensions (3D) using optimized passive clearing methods. This manuscript demonstrates these procedures for passive optical clearing followed by multiple immunofluorescence staining to identify key elements of the autonomic and sensory neural networks innervating human islets.

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