Permanent Teeth

Permanent teeth are the second set of human teeth, highly mineralized organs that replace primary teeth and support biting, chewing, speech, and oral function throughout adulthood. They develop through odontogenesis, in which interactions between oral epithelium and underlying mesenchyme organize tooth tissues; ameloblasts produce enamel, odontoblasts form dentin, and eruption generally accompanies root development and the shedding of primary teeth. Most adults have up to 32 permanent teeth, including third molars, although the number and timing of eruption vary. Studying permanent teeth helps explain craniofacial development, dental anatomy, occlusion, tooth decay, developmental abnormalities, and clinical approaches to oral health.

Permanent Teeth - Related Videos

Research

JoVE Journal - Medicine

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

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Cited by 100 •

2012

The method described isolation and characterization of human Dental Pulp Stem Cells (hDPSCs) by using either enzymatic dissociation of pulp (DPSC-ED) or direct outgrowth of stem cells from pulp tissue explants (DPSC-OG). Then followed by in vitro comparative differentiation of both types of hDPSCs into odontoblasts.

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

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Cited by 6 •

2024

This protocol emphasizes the extraction, culture, and preservation of multipotent stem cells from dental pulp through enzymatic digestion. Additionally, it demonstrates their potential to differentiate into osteoblasts, adipocytes, and chondrocytes, highlighting the importance of precision and consistency in the process.

Education

JoVE Core - Anatomy and Physiology

Teeth

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2024

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage. In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...

Isolation of Gingival Immune Cell Network from Murine Teeth Blocks

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2025

This video demonstrates the isolation procedure of the gingival immune cell network from a mouse model. The enzymatic digestion releases the gingival tissue from the attached teeth and bone, which is further mechanically digested, releasing immune cells from the gingiva. The isolated cells are ready for immunological experiments.

Permanent Income Hypothesis

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2025

The Permanent Income Hypothesis (PIH), formulated by economist Milton Friedman, explains how individuals plan their consumption based on long-term income expectations rather than current earnings. This theory is fundamental for analyzing consumer behavior over time.Friedman separated total income into two parts: permanent income and transitory income.Permanent income represents the average income individuals expect throughout their lives, accounting for predictable and stable...

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