Sigmoid Sinus Exposure

Sigmoid sinus exposure is a surgical technique that reveals the sigmoid sinus, a curved dural venous channel that drains blood from the brain toward the internal jugular vein, to provide controlled access to nearby structures. During the procedure, bone overlying the sinus is carefully removed, often as part of a mastoid or posterior fossa approach, while the sinus wall and surrounding dura are preserved to maintain venous drainage and limit bleeding. In biology and clinical practice, this anatomy-based method supports procedures involving the temporal bone, cerebellopontine region, or adjacent neurovascular structures, while demonstrating the importance of venous anatomy in surgical planning.

Sigmoid Sinus Exposure - Related Videos

Education

JoVE Science Education - Clinical Skills

Nose, Sinuses, Oral Cavity and Pharynx Exam

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2023

Source: Richard Glickman-Simon, MD, Assistant Professor, Department of Public Health and Community Medicine, Tufts University School of Medicine, MA This video provides an overview of sinus, nose, and throat examinations. The demonstration begins with a brief overview of the anatomy of the region. The upper third of the nose is bony, and the bottom two-thirds are cartilaginous. Air entering the nares passes through the nasal vestibules and into the narrow passageway between the nasal septum...

Research

JoVE Journal - Medicine

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus

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Cited by 51 •

2013

We describe procedures to quantify and characterize atherosclerotic lesions in mouse models using precision sectioning of the aortic sinus and ascending aorta combined with histochemical and immunohistochemical analysis.

Research

JoVE Journal - Neuroscience

Establishment of a Modified Ferric Chloride-Induced Superior Sagittal Sinus Thrombosis

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2025

This study presents a protocol for establishing a reproducible, minimally invasive rat model of superior sagittal sinus thrombosis induced by ferric chloride, utilizing a silk-suture method in combination with laser speckle contrast imaging and high-resolution ultrasound for evaluation.

Formation of Human Prostate Epithelium Using Tissue Recombination of Rodent Urogenital Sinus Mesenchyme and Human Stem Cells

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Cited by 10 •

2013

To unravel the earliest molecular mechanisms underlying prostate cancer initiation, novel and innovative human model systems and approaches are desperately needed. The potential of pre-prostatic urogenital sinus mesenchyme (UGSM) to induce pluripotent stem cell populations to form human prostate epithelium is a powerful experimental tool in prostate research.

Developing a Salivary Antibody Multiplex Immunoassay to Measure Human Exposure to Environmental Pathogens

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Cited by 11 •

2016

In the current climate of scarce resources, new technologies are emerging that allow researchers to conduct studies cheaper, faster and with more precision. Here we describe the development of a bead-based salivary antibody multiplex immunoassay to measure human exposure to multiple environmental pathogens simultaneously.

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