Skull Sutures

Skull sutures are immovable or slightly flexible fibrous joints that connect the bones of the skull and protect the developing brain. Dense connective tissue and interlocking bone edges stabilize the cranium while allowing limited movement during birth and gradual expansion as the brain grows. Major sutures, including the coronal, sagittal, lambdoid, and squamous sutures, serve as important anatomical landmarks in biology, medicine, and imaging. Their normal development supports head growth, whereas premature fusion, known as craniosynostosis, can restrict skull expansion and lead to abnormal cranial shape or increased pressure within the skull.

Skull Sutures - Related Videos

Education

JoVE Core - Anatomy and Physiology

Sutures of the Skull

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2025

The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures. Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...

Research

JoVE Journal - Neuroscience
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A Method to Make a Craniotomy on the Ventral Skull of Neonate Rodents

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Cited by 6 •

2014

A surgical method is described to expose the ventral skull in neonate rats. Using this approach it is possible to open a craniotomy to perform acute electrophysiology and two-photon microscopy experiments in the brainstem of anesthetized pups.

Chronic Imaging of Mouse Visual Cortex Using a Thinned-skull Preparation

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Cited by 20 •

2010

In this video and supplemental material, we show a protocol for chronic in vivo imaging of the intact brain using a thinned-skull preparation.

Q Suture Technique: A Suturing Technique to Reduce Gap Formation and Increase Tensile Strength in Tendon Repair

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2025

In this video, we demonstrate suturing techniques — core suture and Q suture — to repair the foot flexor tendon in an ex vivo porcine model. Q sutures enhance the strength of the core suture in tendon repair and decrease gapping at the tendon repair site.

Isolating Immune Cells from Mouse Brain and Skull

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Cited by 1 •

2024

To investigate the immune response to brain disorders, one common approach is to analyze changes in immune cells. Here, two simple and effective protocols are provided for isolating immune cells from murine brain tissue and skull bone marrow.

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