Surgical Glue Application
Surgical Glue Application - Related Videos
08:40
TAPE: A Biodegradable Hemostatic Glue Inspired by a Ubiquitous Compound in Plants for Surgical Application
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Cited by 12 •
2016
We describe the simplest protocol to prepare biodegradable medical glue that has an effective hemostatic ability. TAPE is a water-immiscible supramolecular aggregate prepared by mixing of tannic acid, a ubiquitous compound found in plants, and poly(ethylene) glycol, yielding a 2.5 times greater water-resistant adhesion compared with commercial fibrin glue.
06:15
A Hydrogel Construct and Fibrin-based Glue Approach to Deliver Therapeutics in a Murine Myocardial Infarction Model.
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Cited by 8 •
2015
This protocol aims to alleviate the limitation of poor cell engraftment for stem cell treatment of myocardial infarctions through the use of a hydrogel system and a fibrin-based glue. With this approach, cell-to-tissue contact post-infarction can be maintained, increasing the therapeutic potential of beneficial agents at the site of injury.
06:09
Piezo High Accuracy Surgical Osteal Removal (PHASOR): A Technique for Improved Cranial Window Surgery in Mice
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Cited by 3 •
2018
Piezoelectric surgery has led to improvements in human maxillofacial and dental surgery. We have developed a protocol to optimize piezoelectric surgery for cranial window surgery in mice.
09:15
Creation of Patient-Specific Silicone Cardiac Models with Applications in Pre-surgical Plans and Hands-on Training
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Cited by 10 •
2022
Patient-specific models improve surgeon and fellow confidence when developing or learning surgical plans. Three-dimensional (3D) printers generate adequate detail for surgical preparation, but fail to replicate tissue haptic fidelity. A protocol is presented detailing the creation of patient-specific, silicone cardiac models, combining 3D printing precision with simulated silicone tissue.
08:05
Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
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Cited by 1 •
2022
Here, we present a protocol to treat the great saphenous vein (GSV) and the small saphenous vein (SSV) affected by severe pathological reflux, using an original sclerosing and embolizing cyanoacrylate-based glue composed of N-butyl cyanoacrylate and methacryloxy sulfolane (NBCA+MS).
FAQs
Moisture initiates or supports curing when the adhesive contacts tissue, allowing it to polymerize and form a continuous film. This reaction is central to the method because the cured layer must remain attached while tissue edges stay approximated. In biological studies, observing this behavior helps researchers assess whether an adhesive performs consistently under the wet conditions found at wound surfaces.
A flexible film can hold approximated tissue edges while accommodating movement at the surface of the wound. This property distinguishes the adhesive layer from a purely rigid covering and supports its role as both a closure material and a protective barrier. Researchers evaluating tissue adhesives therefore consider whether curing produces a film that maintains coverage without compromising the repaired area.
Surgical glue application provides an alternative or complement to sutures and staples for closing superficial incisions. Instead of using mechanical fasteners alone, it creates a cured adhesive film across approximated tissue edges. This comparison is useful in research because investigators can examine whether adhesive closure supports wound protection, tissue repair, or less invasive closure procedures under defined experimental conditions.
Performance depends on how well the tissue edges are approximated, how the material cures on contact with moisture, and whether the resulting film remains attached and flexible. Material compatibility with tissue is also important when evaluating biological responses. These factors guide comparisons among adhesive designs and help explain differences in closure quality, protection from contamination, and tissue-repair outcomes.
The procedure begins by bringing the tissue or incision edges together, followed by placing the adhesive along the approximated surface. The material then cures or polymerizes in contact with moisture and forms a film over the closure. This workflow allows the adhesive to hold the surface together while providing coverage, making edge alignment and controlled placement important parts of the application.
Researchers may select this approach when studying wound healing, tissue repair, or the compatibility of biomaterials with tissue. It can also support investigations of materials intended to reduce invasive closure procedures. By examining how a film forms, remains attached, and protects the surface, studies can compare closure strategies and evaluate whether a candidate adhesive is suitable for biological use.
The method can provide information about closure performance, tissue-material compatibility, and the behavior of materials designed to improve healing. Investigators may assess whether the adhesive maintains approximated edges, forms a protective film, and functions during tissue-repair studies. It is also relevant when evaluating applications such as superficial incision closure, graft securing, or device stabilization.