Thoracic Duct

The thoracic duct is the largest lymphatic vessel in the body, collecting lymph and intestinal chyle and returning them to the bloodstream, making it essential for fluid balance, fat transport, and immune surveillance. It typically begins at the cisterna chyli, ascends through the thorax, and empties into the junction of the left internal jugular and subclavian veins; valves, vessel contraction, skeletal-muscle movement, and breathing help drive one-way flow. In biology and medicine, its anatomy supports the study of lymphatic circulation, lipid absorption, metastatic spread, and disorders such as chylothorax, while guiding imaging and surgical management.

Thoracic Duct - Related Videos

Research

JoVE Journal - Biology

Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct

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Cited by 12 •

2010

This video shows how to surgically obstruct the guinea pig's endolymphatic duct to produce endolymphatic hydrops.

Transaxillary First Rib Resection for Treatment of the Thoracic Outlet Syndrome

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Cited by 3 •

2020

Here, we present a protocol of the transaxillary resection of the first rib for treatment of thoracic outlet syndrome caused by compression of the brachial plexus, subclavian vein and artery.

Education

JoVE Core - Anatomy and Physiology

Thoracic Aorta

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2024

The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...

Cannulation of the Mouse Submandibular Salivary Gland via the Wharton's Duct

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Cited by 17 •

2011

A protocol for the cannulation of the mouse submandibular salivary gland via the Wharton's duct is described. For this experiment, the trypan blue solution is used as a dyer to demonstrate how this technique effectively delivers infusions into the targeted gland, and to suggest the reliability of this new approach as a potential clinical drug/cell therapy for the regeneration of salivary glands.

The Thoracic Cage: Sternum

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2023

The thoracic or rib cage forms the body's thorax (chest) portion. Its primary function in the body is to protect vital organs in the thoracic cavity, such as the heart and the lungs. It consists of 12 pairs of ribs with their costal cartilages and the sternum. The ribs are anchored posteriorly to the 12 thoracic vertebrae (T1-T12). The sternum is the elongated bony structure on the anterior side of the thoracic cage. It consists of three parts: the manubrium, the body, and the xiphoid process.

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