Time-lapse Video

Time-lapse video is an imaging method that records a sequence of still images over time and displays them as continuous motion, making gradual biological changes easier to observe. An imaging system captures specimens at defined intervals under consistent conditions, then assembles the frames to show changes in position, shape, behavior, or organization. In biology, this approach can reveal cell division, cell migration, tissue development, organismal growth, and interactions that may be missed during single observations. Time-lapse recordings also support measurements of event timing and movement, helping researchers connect dynamic processes with underlying cellular and developmental mechanisms.

Time-lapse Video - Related Videos

Research

JoVE Journal - Biology

Quantitative Analysis of Random Migration of Cells Using Time-lapse Video Microscopy

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Cited by 26 •

2012

This method allows monitoring of cells in real time and quantitative measurements of different cell migration parameters such as speed, displacement, and velocity. Unlike the traditional methods, this real time approach is not based on endpoint quantitative migration measurements; instead it allows monitoring and calculating different parameters continuously.

Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy

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Cited by 4 •

2016

Herein, we describe in detail a time-lapse video microscopy approach to measuring the temporal recruitment of EYFP-Parkin during the selective removal of damaged mitochondria. This dynamic process of EYFP-Parkin-dependent removal of damaged mitochondria can be used as an indicator of cellular health under different experimental conditions.

Research

JoVE Journal - Biology
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Time-lapse Imaging of Mitosis After siRNA Transfection

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Cited by 8 •

2010

Here we describe a basic protocol to image and quantify the mitotic timing of live mammalian tissue culture cells after siRNA transfection.

Research

JoVE Journal - Biology
Free Sample

Time-lapse Microscopy of Early Embryogenesis in Caenorhabditis elegans

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Cited by 8 •

2011

This article describes a technique for the visualization of the early events of embryogenesis in the nematode Caenorhabditis elegans.

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