Urethral Orifice
Urethral Orifice - Related Videos
05:09
Urethral Stricture Induction Followed by Buccal Mucosa Graft Urethroplasty in a Rat Model
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Cited by 3 •
2023
In the present protocol, a urethral stricture induction was developed in Wistar rats, followed by urethral reconstruction with a buccal mucosa graft. A retrograde urethrogram and laser Doppler assessment were performed, validating urethral reconstruction (after stricture formation) and graft placement.
07:42
Nerve-sparing Mid-urethral Obstruction (NeMO) in Female Small Rodents
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Cited by 7 •
2017
Traditional modeling of partial bladder outlet obstruction in rodents is fraught with animal mortality. A denervation injury from dissection around the proximal urethra and bladder neck is also of major concern. We developed and evaluated a safe and reliable mid-urethral obstruction model, avoiding the shortcomings of the traditional model.
02:54
Establishment of a Urinary Tract Infection Model in Female Mice
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2025
This video demonstrates the establishment of uropathogenic Escherichia coli infection in a female mouse bladder through transurethral catheter instillation. The injected bacteria successfully establish a urinary tract infection within the bladder, providing a valuable platform for studying healthcare-associated diseases related to the urinary tract.
03:56
Delivery of DNA Plasmids into Urothelium of Mouse Bladder: An Electroporation-based Procedure to Efficiently Deliver DNA Plasmids into Urothelial Cells of Murine Bladder to Generate Genetically Engineered Models
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2023
This video demonstrates the delivery of DNA plasmid into the urothelium of the mouse bladder using a combination of urethral catheterization and electroporation techniques. The described procedure allows the generation of mouse bladder cancer models.
08:26
Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
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Cited by 1 •
2023
Here, we present a protocol to successfully perform single-surgeon, three-port, laparoscopic resection for colorectal cancer with natural orifice specimen extraction.
FAQs
Urine passage depends on coordinated activity rather than movement through the urethra alone. The bladder detrusor muscle contracts, while the internal and external urethral sphincters relax to permit flow toward the external opening. This coordination links bladder emptying with control of the outlet and is therefore important for understanding normal urination and continence.
The two sphincters regulate access to the urethral outlet by controlling whether the urethra remains closed or allows urine to pass. Their relaxation must accompany detrusor contraction for effective emptying, whereas their coordinated control supports continence. Studying both structures helps explain how urinary flow is regulated at the outlet rather than treating the orifice as an isolated opening.
Its position and surrounding tissues differ between females and males, making sex-specific anatomy important when studying the urinary tract. In males, the urethral passage has an additional reproductive role because it can convey semen during ejaculation. These anatomical and functional differences provide context for examining urinary anatomy and sexual physiology together.
The external opening is clinically relevant when considering disorders that affect urinary passage, including urinary tract infection and obstruction. Its relationship to the urethra and surrounding tissues makes it part of the anatomical pathway assessed when investigating these conditions. Understanding this connection helps relate symptoms or impaired flow to the urinary tract rather than to the bladder alone.
Clinical examination can use the urethral orifice as an accessible point for assessing relevant urinary anatomy and identifying findings associated with urinary disorders. Because its position and surrounding tissues differ between females and males, examination requires attention to sex-specific anatomy. This anatomical knowledge supports a more accurate interpretation of the urinary outlet during clinical assessment.
Catheter placement depends on recognizing the external urethral opening as the access point to the urethra and urinary tract. Knowledge of its location and surrounding anatomy helps guide this procedure, while awareness of sex-related anatomical differences provides essential context. The same understanding also connects catheterization with broader study of urinary anatomy and clinical management of urinary problems.