Voronoi Tessellation

Voronoi tessellation is a geometric method for partitioning space into regions according to proximity, creating a boundary around each seed point that is closer to it than to any other. In biology, seed points can represent cells, organisms, or localized structures, allowing the resulting polygons to approximate territories and spatial relationships within a tissue or population. By converting spatial positions into measurable regions, Voronoi tessellation supports analysis of cell packing, neighborhood organization, growth patterns, and resource distribution, while providing a simple framework for comparing biological arrangements across conditions.

Voronoi Tessellation - Related Videos

Research

JoVE Journal - Bioengineering

Stepwise Cell Seeding on Tessellated Scaffolds to Study Sprouting Blood Vessels

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2021

Engineered tissues heavily rely on proper vascular networks to provide vital nutrients and gases and remove metabolic waste. In this work, a stepwise seeding protocol of endothelial cells and support cells creates highly organized vascular networks in a high-throughput platform for studying developing vessel behavior in a controlled 3D environment.

Mapping Absolute DNA Density in Cell Nuclei using Single-molecule Localization Microscopy

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2025

The present protocol describes a method measuring absolute DNA densities within adherent cell nuclei using Voronoi tessellation of single-molecule localization microscopy data, known volume, genome size, and cell cycle stage.

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells

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Cited by 6 •

2016

Two assays for microscopy-based high-throughput screening of host factors involved in Brucella infection are described. The entry assay detects host factors required for Brucella entry and the endpoint assay those required for intracellular replication. While applicable for alternative approaches, siRNA screening in HeLa cells is used to illustrate the protocols.

High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain

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Cited by 8 •

2012

This article describes techniques to perform high-resolution functional magnetic resonance imaging with 1.2 mm sampling in human midbrain and subcortical structures using a 3T scanner. Use of these techniques to resolve topographic maps of visual stimulation in the human superior colliculus (SC) is given as an example.

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section

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Cited by 4 •

2016

Stent implants in stenosed arterial curvatures are prone to "Type IV" failures involving the complete transverse fracture of stents and linear displacement of the fractured parts. We present a protocol for detection of secondary flow (vortical) structures in a curved artery model, downstream of clinically relevant "Type IV" stent failures.

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