Arterial Structural Changes
Arterial Structural Changes - Related Videos
10:33
Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
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Cited by 34 •
2014
Right ventricle (RV) dysfunction is critical to the pathogenesis of cardiovascular disease, yet limited methodologies are available for its evaluation. Recent advances in ultrasound imaging provide a noninvasive and accurate option for longitudinal RV study. Herein, we detail a step-by-step echocardiographic method using a murine model of RV pressure overload.
06:51
Multilevel Microdissection and Functional-Structural Profiling of Human Renal Arterial Branches
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2025
This article presents a step-by-step protocol for the isolation and functional evaluation of human renal arterial branches, facilitating preclinical studies for pharmaceutical development.
11:00
Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section
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Cited by 4 •
2016
Stent implants in stenosed arterial curvatures are prone to "Type IV" failures involving the complete transverse fracture of stents and linear displacement of the fractured parts. We present a protocol for detection of secondary flow (vortical) structures in a curved artery model, downstream of clinically relevant "Type IV" stent failures.
06:57
Arterial Line Placement
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2023
Source: Sharon Bord, MD, Department of Emergency Medicine, The Johns Hopkins University School of Medicine, Maryland, USA When monitoring patients, it is important to obtain values that are accurate and reliable. Blood pressure monitoring is one of the essential vital signs, and for a majority of patients, measuring it utilizing non-invasive techniques provides accurate values. However, there are situations in which the blood pressure requires more exact, specific, and reliable measurements.
13:10
Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)
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Cited by 7 •
2017
Surgical correction of ALCAPA is highly recommended, regardless of age or the degree of intercoronary collateralization. This protocol presents a technique for the direct re-implantation of adult-type ALCAPA into the aorta to re-establish the dual-coronary perfusion. Whenever feasible, direct re-implantation is preferred to other surgical correction techniques.
FAQs
These processes can initiate or reinforce remodeling within the arterial wall. Endothelial injury may alter the vessel’s normal interface with blood, while inflammation and lipid accumulation contribute to changes in wall organization. Smooth muscle remodeling and extracellular matrix alterations can then modify the vessel’s physical properties, helping explain how disease-related structural changes develop and persist.
Arterial elasticity helps vessels accommodate physiological demands, whereas the lumen provides the passageway for blood. When structural changes reduce elasticity or narrow the lumen, the artery may transport blood less effectively and respond differently to changing demands. Measuring these features therefore helps clinicians characterize vascular disease and evaluate its potential effect on circulation.
Smooth muscle remodeling can change the organization and physical behavior of the arterial wall, while extracellular matrix changes can affect its supporting structure. Together, these alterations may contribute to reduced elasticity or other changes in vessel architecture. Their assessment is relevant when examining conditions such as hypertension-related vascular remodeling, atherosclerosis, and aneurysms.
Clinical assessment can combine imaging, vascular measurements, and tissue analysis. Imaging helps visualize vessel architecture and identify changes in the arterial wall or lumen. Vascular measurements provide information about vessel characteristics, while tissue analysis examines structural organization. Using these approaches together can reveal disease-related changes and support a more complete evaluation of vascular status.
Evaluation is useful when clinicians need to characterize conditions associated with altered arterial structure, including atherosclerosis, hypertension-related vascular remodeling, and aneurysms. Findings from imaging, vascular measurements, or tissue analysis can help indicate disease progression and support risk assessment. This information may contribute to decisions about strategies intended to preserve blood flow and reduce cardiovascular complications.
Structural assessments provide evidence about the state of the vessel wall, lumen, and overall arterial organization. By showing disease progression or identifying features associated with impaired blood transport, they can help clinicians evaluate the need for strategies aimed at preserving blood flow. In clinical research and care, these findings also support monitoring of vascular disorders over time.