O2 Conserving Cannula

An O2 conserving cannula is a specialized nasal cannula that delivers supplemental oxygen while reducing oxygen waste, helping patients use portable or stationary supplies more efficiently. Its reservoir stores oxygen during exhalation and releases a concentrated bolus at the beginning of the next inhalation, when it can reach the lungs; some systems coordinate delivery with the patient’s inspiratory effort. By extending cylinder duration and supporting ambulatory oxygen therapy, this device can improve mobility and simplify long-term oxygen administration for people with chronic respiratory conditions. Clinical selection and adjustment require assessment of breathing pattern, oxygen saturation, activity level, and prescribed flow requirements.

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JoVE Science Education - Physics

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2023

Source: Nicholas Timmons, Asantha Cooray, PhD, Department of Physics & Astronomy, School of Physical Sciences, University of California, Irvine, CA The goal of this experiment is to test the concept of the conservation of momentum. By setting up a surface with very little friction, collisions between moving objects can be studied, including their initial and final momenta. The conservation of momentum is one of the most important laws in physics. When something is conserved in physics, the...

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JoVE EoE - Neurotherapeutics

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Source: Xavier, A. L. R., et al. Cannula Implantation into the Cisterna Magna of Rodents. J. Vis. Exp. (2018)This video demonstrates the procedure for implanting a cannula into the cisterna magna of an anesthetized mouse. The technique involves guiding a needle-mounted cannula through the dura into the inverted triangular cisterna magna and securing it for targeted delivery into the cerebrospinal fluid.

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Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function. Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally analyses the...

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Oxygen therapy is critical to patient care, especially for those struggling with respiratory issues. This intervention increases the oxygen concentration in the lungs, enhancing the amount of oxygen transported to the body's tissues. One standard method of delivering supplemental oxygen is through a nasal cannula, a non-invasive device that provides low to medium oxygen concentrations. Nasal Cannulas A nasal cannula is a lightweight tube split into two prongs placed in the nostrils, connected...

Conservation of Energy Approach to System Analysis

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2023

Source: Ricardo Mejia-Alvarez and Hussam Hikmat Jabbar, Department of Mechanical Engineering, Michigan State University, East Lansing, MI The purpose of this experiment is to demonstrate the application of the energy conservation equation to determine the performance of a flow system. To this end, the energy equation for steady, incompressible flow is applied to a short pipe with a gate valve. The gate valve is then gradually closed and its influence on flow conditions is characterized. In...

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