Vastus Lateralis
Vastus Lateralis - Related Videos
07:16
Human Vastus Lateralis Skeletal Muscle Biopsy Using the Weil-Blakesley Conchotome
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Cited by 18 •
2016
This video demonstrates the technique of percutaneous muscle biopsy of the human vastus lateralis using the Weil-Blakesley conchotome.
20:14
Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord
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Cited by 21 •
2009
Traumatic injury to the spinal cord disrupts communication with the brain. To restore lost connectivity we utilize a peripheral nerve graft to provide a substratum for regenerating fibers in combination with neurotrophic factors and matrix-modulating enzymes to remove inhibitory molecules to promote long distance growth.
06:38
Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
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Cited by 12 •
2016
Although mouse models are invaluable tools for bone tissue engineering, models of long bone defects are sparse. This need motivated development of the present protocol which uses a locking plate with four screws and a dedicated jig to perform and stabilize a reproducible, femoral, critical-size defect with low morbidity.
08:44
Activating Autophagy by Aerobic Exercise in Mice
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Cited by 37 •
2017
Autophagy activation is beneficial in the prevention of a number of diseases. One of the physiological approaches to induce autophagy in vivo is physical exercise. Here we show how to activate autophagy by aerobic exercise and measure autophagy levels in mice.
03:47
Inducing Fibular Nerve Injury in a Mouse to Study Neuromuscular Junction Regeneration
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2025
Source: Dalkin, W., et al. The Fibular Nerve Injury Method: A Reliable Assay to Identify and Test Factors That Repair Neuromuscular Junctions. J. Vis. Exp. (2016)This video demonstrates a surgical procedure to induce fibular nerve injury in a mouse to study neuromuscular junction (NMJ) regeneration. The procedure involves exposing the fibular nerve, applying controlled pressure to induce injury, and ensuring the epineurium remains intact to support axonal regeneration. Over time, macrophages...
FAQs
During knee extension, activation of the vastus lateralis transmits force through the quadriceps tendon and patellar ligament to the tibial tuberosity. This force straightens the knee, while its relationship with the patella helps maintain patellar stability during movement. Because the other quadriceps muscles act with it, effective extension depends on coordinated recruitment rather than this muscle alone.
Femoral nerve activation provides the neural signal required for the vastus lateralis to contract. Clinically, weakness involving this muscle can therefore provide information about lower-limb motor function and possible impairment of femoral nerve integrity. Interpreting the finding in relation to the quadriceps is important because knee extension depends on coordinated activity among several muscles.
The vastus lateralis contributes to functional knee control by working with the other quadriceps muscles. Their coordinated contraction supports knee extension during activities such as standing, walking, and rising. This shared action explains why difficulty with these movements may reflect impaired quadriceps performance rather than an isolated problem in a single muscle.
Its broad, accessible muscle mass makes the vastus lateralis a practical site for intramuscular injections. The available tissue on the lateral thigh supports its clinical use when an injection must be delivered into muscle. This anatomical accessibility is especially relevant in routine care involving infants and young children.
The vastus lateralis is especially useful for intramuscular injections in infants and young children because it provides a broad muscle mass that is accessible on the lateral thigh. Its clinical value in these age groups reflects the combination of suitable muscle tissue and straightforward anatomical access, rather than its role in knee movement alone.
Assessing vastus lateralis strength can help clinicians evaluate lower-limb function and consider the integrity of the femoral nerve. The finding is relevant because contraction contributes to knee extension, a movement required for standing, walking, and rising. Strength assessment therefore connects a local muscle response with broader functional performance of the lower limb.