Construction Engineering

Construction engineering is the engineering discipline that plans, coordinates, and controls the processes used to create buildings, transportation systems, and other infrastructure, linking design decisions with safe, buildable outcomes. It works by translating project requirements and structural or civil designs into construction methods, material selections, equipment operations, schedules, and quality controls while accounting for site conditions, loads, resources, and safety constraints. Construction engineers apply these principles to foundations, concrete and steel systems, earthwork, and infrastructure projects, helping reduce risk, manage cost and time, improve durability, and support sustainable development through better planning and construction technologies.

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Research

JoVE Journal - Biology

Fabrication of Myogenic Engineered Tissue Constructs

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Cited by 11 •

2009

Here, we demonstrate fabrication of collagen-based, tissue constructs containing skeletal myoblasts. These 3-D engineered constructs may be used to replace or repair tissues in vivo. For our purposes, we have designed these as an atrioventricular electrical conduit for the repair of complete heart block[1].

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

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Cited by 16 •

2012

The procedure demonstrates the methodology of magnetic resonance elastography for monitoring the engineered outcome of adipose and osteogenic tissue engineered constructs through noninvasive local assessment of the mechanical properties using microscopic magnetic resonance elastography (μMRE).

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

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Cited by 2 •

2014

For creation of highly organized structures of complex tissue, one must assemble multiple material and cell types into an integrated composite. This combinatorial design incorporates organ-specific layered cell sheets with two distinct biologically-derived materials containing a strong fibrous matrix base, and endothelial cells for enhancing new vessels formation.

Engineering Fibrin-based Tissue Constructs from Myofibroblasts and Application of Constraints and Strain to Induce Cell and Collagen Reorganization

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Cited by 5 •

2013

This model system starts from a myofibroblast-populated fibrin gel that can be used to study endogenous collagen (re)organization real-time in a nondestructive manner. The model system is very tunable, as it can be used with different cell sources, medium additives, and can be adapted easily to specific needs.

Constructing a Humanized Mouse Model with Engineered Immunity against HIV

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2025

The video demonstrates a technique to generate a humanized mouse model with stem-cell-based engineered immunity against the human immunodeficiency virus (HIV). Human fetal thymus tissue and engineered hematopoietic stem cells (HSCs) are implanted into the kidney capsule of a severely immunocompromised mouse. The HSCs, which express chimeric antigen receptors (CARs) against HIV, are mixed in a gelatinous protein mixture that promotes their co-localization with thymus tissue. Post-procedure, the...

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