Simulation Model Build

Simulation model build is the structured process of translating a real engineering system, process, or physical phenomenon into a computational representation for analysis and prediction. Engineers define system boundaries, assumptions, inputs, governing relationships, and outputs, then implement and verify the model using suitable mathematical, logical, or numerical methods. Calibration against experimental or operational data can improve agreement between simulated and observed behavior, while validation assesses whether the model supports its intended purpose. Simulation models help engineers evaluate designs, test operating conditions, identify performance limits, and compare alternatives before committing resources to physical prototypes or field trials.

Simulation Model Build - Related Videos

Research

JoVE Journal - Developmental Biology
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Building Finite Element Models to Investigate Zebrafish Jaw Biomechanics

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Cited by 19 •

2016

Finite Element Analysis is a frequently used tool to investigate the mechanical performance of structures under load. Here we apply its use to modeling the biomechanics of the zebrafish jaw.

Research

JoVE Journal - Medicine

A Model to Simulate Clinically Relevant Hypoxia in Humans

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Cited by 1 •

2016

Hypoxia simulation in humans has usually been performed by inhaling hypoxic gas mixtures. For this study, apneic divers were used to simulate dynamic hypoxia in humans. Additionally, physiological changes in desaturation and re-saturation kinetics were evaluated with non-invasive tools such as Near-Infrared-Spectroscopy (NIRS) and peripheral oxygenation saturation (SpO2).

Modeling and Simulations of Olfactory Drug Delivery with Passive and Active Controls of Nasally Inhaled Pharmaceutical Aerosols

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Cited by 18 •

2016

This manuscript reviews the modeling and simulations of different protocols to deliver medications to the olfactory region in image-based nasal airway models. Multiple software modules are used to develop the anatomically accurate nose model, generate computational mesh, simulate nasal airflows, and predict particle deposition at the olfactory region.

Analyzing and Building Nucleic Acid Structures with 3DNA

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Cited by 63 •

2013

The 3DNA software package is a popular and versatile bioinformatics tool with capabilities to analyze, construct, and visualize three-dimensional nucleic acid structures. This article presents detailed protocols for a subset of new and popular features available in 3DNA, applicable to both individual structures and ensembles of related structures.

Designing and Implementing Nervous System Simulations on LEGO Robots

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Cited by 7 •

2013

An approach to neural network modeling on the LEGO Mindstorms robotics platform is presented. The method provides a simulation tool for invertebrate neuroscience research in both the research lab and the classroom. This technique enables the investigation of biomimetic robot control principles.

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