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Analyzing and Building Nucleic Acid Structures with 3DNA
JoVE Journal
Biology
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JoVE Journal Biology
Analyzing and Building Nucleic Acid Structures with 3DNA
DOI:

16:24 min

April 26, 2013

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Chapters

  • 00:05Title
  • 01:49Installation of the Software Package
  • 04:02Analysis of a Crystal Structure
  • 05:22Construction of a DNA Structure from Rigid-body Parameters
  • 06:38Analysis of Multi-model Structure Files
  • 08:15Superposition of Multi-model Structures onto a Common Reference Frame
  • 09:29Construction of a Protein-decorated DNA Molecule
  • 11:54Results: Nucleic Acid Structure Analysis and Reconstruction with 3DNA
  • 15:52Conclusion

Summary

Automatic Translation

The 3DNA software package is a popular and versatile bioinformatics tool with capabilities to analyze, construct, and visualize three-dimensional nucleic acid structures. This article presents detailed protocols for a subset of new and popular features available in 3DNA, applicable to both individual structures and ensembles of related structures.

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