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A Model to Simulate Clinically Relevant Hypoxia in Humans
 

A Model to Simulate Clinically Relevant Hypoxia in Humans

Article DOI: 10.3791/54933-v 09:54 min December 22nd, 2016
December 22nd, 2016

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Summary

Hypoxia simulation in humans has usually been performed by inhaling hypoxic gas mixtures. For this study, apneic divers were used to simulate dynamic hypoxia in humans. Additionally, physiological changes in desaturation and re-saturation kinetics were evaluated with non-invasive tools such as Near-Infrared-Spectroscopy (NIRS) and peripheral oxygenation saturation (SpO2).

Tags

Simulate Clinically Relevant Hypoxia Apnoea Hypercapnia Intermittent Apnoea Sleep Apnoea Airway Obstruction Physiological Mechanisms Hypoxic Damage Dynamic Model Heart Rate Circulation Technical Devices NIRS Electrode Peripheral Tissue Oxygenation Cerebral Tissue Oxygenation
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