Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
JoVE Journal

A subscription to JoVE is required to view this content.

A Model to Simulate Clinically Relevant Hypoxia in Humans

A Model to Simulate Clinically Relevant Hypoxia in Humans

Article DOI: 10.3791/54933-v 09:54 min December 22nd, 2016
December 22nd, 2016



Hypoxia simulation in humans has usually been performed by inhaling hypoxic gas mixtures. For this study, apneic divers were used to simulate dynamic hypoxia in humans. Additionally, physiological changes in desaturation and re-saturation kinetics were evaluated with non-invasive tools such as Near-Infrared-Spectroscopy (NIRS) and peripheral oxygenation saturation (SpO2).


Simulate Clinically Relevant Hypoxia Apnoea Hypercapnia Intermittent Apnoea Sleep Apnoea Airway Obstruction Physiological Mechanisms Hypoxic Damage Dynamic Model Heart Rate Circulation Technical Devices NIRS Electrode Peripheral Tissue Oxygenation Cerebral Tissue Oxygenation
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter