Slate
Slate - Related Videos
05:09
Repetitive Tumor Challenge Assay: An In Vitro Culture Assay to Evaluate Chimeric Antigen Receptor (CAR) T Cells for Repetitive Tumor Killing Potential
0 Views •
2025
In this video, we demonstrate the repetitive tumor challenge assay to evaluate the CAR T cells’ repetitive tumor killing potential during high tumor cell loads. Further, the CAR T cells can be analyzed using flow cytometry to determine the different subpopulations of CAR T cells in the sample.
08:55
Making a Geologic Cross Section
0 Views •
2023
Source: Laboratory of Alan Lester - University of Colorado Boulder Geologic maps were first made and utilized in Europe, in the mid-to-late 18th century. Ever since, they have been an important part of geological investigations all around the world that strive to understand rock distributions on the surface of the earth, in the subsurface, and their modification through time. A modern geologic map is a data-rich representation of rocks and rock-structures in a two-dimensional plan view. The...
10:15
Mouse Short- and Long-term Locomotor Activity Analyzed by Video Tracking Software
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Cited by 27 •
2013
Locomotor activity (LMA) is a simple and easily performed measurement of behavior in mice. Coupling of video tracking software (VTS) and LMA allows for the improvement of specificity and sensitivity, especially when compared with the manual, line crossing method of LMA analysis. Additionally VTS allows long-term tracking of mouse LMA.
09:32
Direct Imaging of ER Calcium with Targeted-Esterase Induced Dye Loading (TED)
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Cited by 60 •
2013
Targeted-esterase induced dye loading (TED) supports the analysis of intracellular calcium store dynamics by fluorescence imaging. The method bases on targeting of a recombinant Carboxylesterase to the endoplasmic reticulum (ER), where it improves the local unmasking of synthetic low-affinity Ca2+ indicator dyes in the ER lumen.
FAQs
During low-grade metamorphism, minerals such as mica and chlorite realign within the original clay-rich rock. This alignment creates slaty cleavage, a pronounced planar structure that allows the material to split into relatively flat sheets. The cleavage direction therefore affects how slate divides and must be considered when evaluating its suitability and orientation in construction applications.
Low porosity contributes to slate’s weather resistance, while cleavage orientation influences its dimensional stability and behavior as thin sheets. These characteristics are not interchangeable: a visually suitable piece may still require evaluation for water absorption, thickness, strength, and cleavage direction. Considering them together helps engineers reduce the risk of unsuitable material selection in long-lasting designs.
Engineers should compare thickness, strength, water absorption, freeze-thaw performance, surface finish, and cleavage orientation. Thickness and strength relate to the material’s structural suitability, while absorption and freeze-thaw performance help assess durability in exposed conditions. Surface finish affects the intended appearance or use. Reviewing these properties together supports a selection matched to the project’s requirements.
Begin by identifying the intended use, such as roofing, flooring, cladding, paving, or an architectural feature. Then assess candidate slate for thickness, strength, water absorption, freeze-thaw performance, surface finish, and cleavage orientation. The results can be compared with the demands of the application, allowing engineers to select material with appropriate durability, appearance, and dimensional stability.
Slate can serve as roofing, flooring, wall cladding, paving, or part of an architectural feature because it combines durability, natural texture, weather resistance, and dimensional stability. The relevant priority changes by application: surface finish and appearance may be important for visible architectural work, while thickness, strength, absorption, and freeze-thaw performance guide durability-focused selection.
Outdoor slate should be evaluated for freeze-thaw performance because engineers need evidence that the selected material can withstand the environmental demands of its intended setting. Water absorption is assessed alongside this property, since both relate to durability considerations. Incorporating these checks into material selection supports longer-lasting roofing, paving, cladding, and other exposed designs.