Toggle Vise
Toggle Vise - Related Videos
05:21
Culturing and Harvesting of HSPC Clones: A Method to Obtain the Singly-Sorted HSPC Clones
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2023
This video describes the protocol for isolating HSPCs from the bone marrow and sorting them using a fluorescent activated cell sorting technique, which is a method to obtain singly-sorted HSPCs. We culture these sorted cells to obtain HSPC clones.
07:12
A Gaze-Contingent Display Framework for Perceptual Learning Research with Simulated Central Vision Loss
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Cited by 1 •
2025
We present development of a gaze-contingent display framework designed for perceptual and oculomotor research simulating central vision loss. This framework is particularly adaptable for studying compensatory behavioral and oculomotor strategies in individuals experiencing both simulated and pathological central vision loss.
14:01
Anesthesia Induction and Maintenance
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2016
Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN The Guide for the Care and Use of Laboratory Animals ("The Guide") states that pain assessment and alleviation are integral components of the veterinary care of laboratory animals. The definition of anesthesia is the loss of feeling or sensation. It is a dynamic event involving changes in anesthetic depth with respect to an animal's metabolism, surgical stimulation, or variations in the...
11:33
Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography
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Cited by 48 •
2016
We present a protocol on how to utilize high-throughput cryo-electron tomography to determine high resolution in situ structures of molecular machines. The protocol permits large amounts of data to be processed, avoids common bottlenecks and reduces resource downtime, allowing the user to focus on important biological questions.
09:33
Determining Cell Number During Cell Culture using the Scepter Cell Counter
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Cited by 56 •
2010
The Scepter Cell Counter is a handheld automated device that can be used to count cells, monitor cell diameter and volume, and be used to check the health and quality of cellular populations from one culture to the next.
FAQs
The linkage’s over-center position is the key to holding. As the vise closes, the hinged members move past their center position, so the resulting geometry resists opening rather than merely relying on continued handle pressure. This converts the operator’s applied motion into clamping force, helping the workpiece remain stable during repeated engineering operations.
Applied handle motion travels through the hinged linkage and emerges as clamping force at the workholding point. The mechanism therefore illustrates mechanical advantage: direct motion at the handle can produce a useful securing action through the linkage geometry. Studying that conversion helps engineers connect vise behavior with broader principles of force transmission and fixture design.
Releasing the handle disengages the workpiece. This matters because the operator can alternate between a secured condition for an operation and an open condition for removal or repositioning. The same linkage that resists opening when over center therefore supports a repeatable clamp-and-release cycle in repetitive work, contributing to consistent handling between successive operations.
An operating cycle consists of positioning the workpiece in the vise, moving the hinged handle until the linkage passes its center position, carrying out the intended operation while the part is secured, and releasing the handle to disengage it. Repeating this sequence provides a consistent setup pattern for tasks in which many parts require similar holding.
Toggle vises are suited to repetitive machining, drilling, assembly, and welding tasks. In each case, the workholding function supports a stable part during the operation and reduces the time spent on repeated setup. Their value is greatest when an engineering workflow requires many cycles with consistent part positioning, rather than a one-time arrangement.
In engineering, the device is useful beyond immediate clamping because its simple linkage makes fixture behavior easier to examine. A user can study how hinged motion, over-center geometry, applied force, and resulting stability are related. That makes the toggle vise a practical example for analyzing force transmission, mechanical advantage, and fixture design in an applied setting.