Chemoattractant Concentration

Chemoattractant concentration is the amount of a chemical signal present in a defined volume, and its spatial variation can guide the movement of cells or microorganisms through an environment. During chemotaxis, receptors detect local concentration changes, allowing organisms to compare signal strength over time or across their surface and bias movement toward increasing concentrations. Concentration gradients arise through diffusion, fluid transport, chemical production, and degradation, so their shape and persistence depend on environmental conditions. Measuring and modeling these gradients helps explain microbial nutrient acquisition, pollutant responses, and the distribution of motile organisms in soil and aquatic habitats.

Chemoattractant Concentration - Related Videos

Research

JoVE EoE - Neuropathology

Assessing Interneuron Response to Chemoattractive Cues from Periventricular Endothelial Cells

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2025

This video shows a method to test interneuron migration in response to chemoattractive cues from periventricular endothelial cells (PVECs). Interneurons are placed in a central compartment, with PVECs and control cells on either side. Increased migration towards PVECs indicates a positive response to their chemoattractive signals.

Volatile Sex Pheromone Extraction and Chemoattraction Assay in Caenorhabditis elegans

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Cited by 1 •

2024

This protocol establishes methods for extracting and quantifying responses to the volatile sex pheromone in C. elegans, providing tools to study chemical communication and navigation trajectory.

Two Types of Assays for Detecting Frog Sperm Chemoattraction

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Cited by 5 •

2011

Eggs and the extracellular coatings around eggs frequently release peptides, proteins and small molecules that communicate with sperm to guide them to the egg thereby promoting fertilization. Using frog sperm we describe and compare two classes of assays used to detect sperm chemoattraction – sperm accumulation assays and sperm tracking assays.

Education

JoVE Core - Chemistry

Concentration Cells

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2020

A concentration cell is a type of a voltaic cell constructed by connecting two almost identical half-cells, both based on the same half-reaction and using the same electrode, differing only in the concentration of one redox species. A concentration cell's potential, therefore, is determined only by the concentration difference of the particular redox species. Consider the following voltaic cell: From the given information, the cell potential of this concentration cell can be calculated using...

3D Analysis of Multi-cellular Responses to Chemoattractant Gradients

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Cited by 4 •

2019

We describe a method to construct devices for 3D culture and experimentation with cells and multicellular organoids. This device allows analysis of cellular responses to soluble signals in 3D microenvironments with defined chemoattractant gradients. Organoids are better than single cells at detection of weak noisy inputs.

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