Anterior Knee Pain

Anterior knee pain is discomfort felt at or around the front of the knee, often reflecting irritation or dysfunction in structures such as the patellofemoral joint, patellar tendon, or surrounding soft tissues rather than a single disease. It commonly develops when repeated loading, altered movement mechanics, muscle weakness, or a sudden increase in activity increases stress on these tissues, producing pain during activities such as squatting, stair climbing, or running. In medicine, assessment combines symptom history, physical examination, and selective imaging to distinguish likely causes and guide treatment, which may include activity modification, targeted exercise, and correction of contributing biomechanics. Understanding its mechanisms supports accurate diagnosis, rehabilitation, and prevention of persistent disability.

Anterior Knee Pain - Related Videos

Education

JoVE Science Education - Clinical Skills

Knee Exam

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2023

Source: Robert E. Sallis, MD. Kaiser Permanente, Fontana, California, USA The knee is a hinged joint that connects the femur with the tibia. It is the largest joint in the body, and due to its location in the middle of the lower leg, it is subjected to a variety of traumatic and degenerative forces. Examination of the knee can be quite complex, owing to the fact it is an inherently unstable joint held together by various ligaments and supported by menisci, which act as shock absorbers and...

Research

JoVE Journal - Biology

Assessment of Knee Hyperalgesia in Mice using Pressure Application Measurement

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Cited by 2 •

2025

The protocol describes how to measure knee hyperalgesia in mice. We show examples in mouse models of acute knee pain as well as in models of osteoarthritis (OA).

Research

JoVE Journal - Medicine
Free Sample

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain

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Cited by 5 •

2019

We have developed an evoked measure of arthritis pain and coupled it with a standardized method for measuring spontaneous pain in different murine models of chemically induced arthritis. These measures are sensitive and reproducible for different types of joint pain.

Research

JoVE Journal - Medicine
Free Sample

Fu's Subcutaneous Needling for Knee Osteoarthritis Pain

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Cited by 8 •

2023

We present a protocol for using Fu's subcutaneous needling for knee osteoarthritis pain, which combines swaying movement and reperfusion approach techniques. This protocol has great potential for future applications in myofascial pain treatment and could enhance Fu's subcutaneous needling (FSN) manipulation skills.

Research

JoVE Journal - Medicine
Free Sample

The Monoiodoacetate Model of Osteoarthritis Pain in the Mouse

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Cited by 181 •

2016

Osteoarthritis (OA), or degenerative joint disease, is a debilitating condition associated with pain that remains only partially controlled by available analgesics. Animal models are being developed to improve our understanding of OA-related pain mechanisms. Here we describe the methodology for the monoiodoacetate model of OA pain in the mouse.

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