Bronchial Brushing
Bronchial Brushing - Related Videos
14:39
Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Cited by 4 •
2010
Bronchial thermoplasty is a non-drug procedure for severe persistent asthma that delivers thermal energy to the airway wall in a precisely controlled manner to reduce excessive airway smooth muscle. Reducing airway smooth muscle decreases the ability of the airways to constrict, thereby reducing the frequency of asthma attacks.
14:32
Primary Human Bronchial Epithelial Cells Grown from Explants
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Cited by 19 •
2010
Here we describe a detailed method for growing primary human bronchial epithelial cells from explants of human bronchial airway tissue including differentiated growth on an air-liquid interface. This method provides an abundant source of primary cells for investigating the role of the airway epithelium in human lung health and disease.
09:50
Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
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Cited by 41 •
2015
The aim of this protocol is to expose human organotypic 3D bronchial and nasal tissue models to mainstream cigarette smoke (CS) at the air-liquid interface. The impact of CS on the tissues is then investigated using a cytochrome P450 activity assay, a cilia beating measurement, and a systems biology approach.
01:23
The Bronchial Tree
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2025
The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components. The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
13:57
Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes
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Cited by 4 •
2014
The methodology to perform friction force microscopy experiments for contacting brushes is presented: Two polymer brushes that are grafted from (a) substrates and (b) colloidal probes are slid to show that, by using two contacting immiscible brush systems, friction in sliding contacts is reduced compared to miscible brush systems.
FAQs
The brush obtains cellular material by contacting the bronchial mucosa rather than relying on a larger tissue fragment. Gentle rotation or sweeping dislodges cells from the targeted area, and the recovered sample becomes the basis for cytologic examination or other laboratory testing. This mechanism is especially useful when an abnormality is visible within a bronchus but conventional tissue sampling is difficult.
The key distinction is the type of specimen collected. Brushing retrieves cells from the airway lining, while a tissue biopsy obtains tissue for examination. Because brushing analyzes recovered cellular material through cytology or other laboratory tests, clinicians may select it when an endobronchial abnormality requires sampling but tissue biopsy is difficult. It provides a practical diagnostic option for selected bronchial findings.
Target selection depends on where an abnormal respiratory finding appears. When imaging identifies an endobronchial lesion, the bronchoscope can direct the brush to that suspicious bronchial area, concentrating sampling on the relevant site. This localization connects the recovered specimen with a specific airway abnormality and helps clinicians interpret laboratory findings within the context of the observed lesion.
The bronchoscope provides access to the bronchial area under investigation. A brush passed through the instrument is guided to the target, then gently rotated or swept across the mucosa. The recovered material is collected and submitted for cytology or another laboratory test. The workflow therefore links airway localization, controlled contact with the mucosa, specimen recovery, and laboratory analysis.
Clinicians may consider this technique when investigating suspected lung cancer, respiratory infections, or other bronchial disorders. Its role is particularly relevant when imaging shows an endobronchial lesion and obtaining a tissue biopsy is difficult. In these settings, the sample can add diagnostic information and may help guide decisions about further testing or treatment.
A bronchial brushing result contributes to diagnostic decision-making rather than standing alone. Cytology or other laboratory findings from the recovered material help assess the suspected lesion or disorder. When considered alongside the broader respiratory evaluation, these results may indicate whether additional testing is needed or inform treatment decisions, allowing the procedure to support both diagnosis and subsequent management planning.