Non Pharmacological Therapy

Non-pharmacological therapy comprises medical interventions that prevent, manage, or relieve disease without using medications, making it an important component of comprehensive patient care. These approaches work through mechanisms such as modifying behavior, improving physical function, supporting psychological adaptation, or changing environmental and social conditions; examples include exercise, nutrition counseling, psychotherapy, physical therapy, and medical devices. In medicine, clinicians select and combine these therapies according to the patient’s condition, goals, and risks. They can reduce symptoms, improve daily functioning and quality of life, support chronic disease management, and complement pharmacological treatment when used within an evidence-based care plan.

Non Pharmacological Therapy - Related Videos

Research

JoVE Journal - Biology

Ole Isacson: Development of New Therapies for Parkinson's Disease

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Cited by 1 •

2007

Ole Isacson gives a concise overview of Parkinsons's disease, its causes, therapeutic strategies, and advances in Parkinson's research.

Research

JoVE Journal - Biology
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Pharmacological and Functional Genetic Assays to Manipulate Regeneration of the Planarian Dugesia japonica

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Cited by 17 •

2011

An attractive model for studying stem cell differentiation within a live animal is the planarian flatworm. Regeneration is studied by simple amputation experiments that are easily performed in a basic laboratory and are amenable to pharmacological and genetic (in vivo RNAi) manipulation as detailed by protocols in this article.

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention

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Cited by 23 •

2013

Loss of the righting reflex has long served as a standard behavioral surrogate for unconsciousness, also called hypnosis, in laboratory animals. Alterations in volatile anesthetic sensitivity caused by pharmacological interventions can be detected with a carefully controlled high-throughput assessment system, which may be adapted for delivery of any inhaled therapeutic.

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

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Cited by 13 •

2013

Epidermal melanin is induced by topical application of forskolin in a murine model of the fair-skinned UV-sensitive human. Pharmacologic manipulation of cAMP levels in the skin and epidermal darkening strongly protect against UV-mediated inflammation (sunburn) as measured by the minimum erythematous dose (MED) assay.

Research

JoVE Journal - Medicine
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The Use of Pharmacological-challenge fMRI in Pre-clinical Research: Application to the 5-HT System

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Cited by 9 •

2012

The goal of this technique is to assess serotonin (5-HT) neurotransmitter function in the live and free-breathing animal with pharmacological magnetic resonance imaging (phMRI) and an intravenous challenge with a selective serotonin reuptake inhibitor (SSRI), fluoxetine.

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