Pancreatic Resection
Pancreatic Resection - Related Videos
10:10
Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms
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2026
This protocol presents robotic duodenum-preserving total pancreatic head resection (R-DPPHRt) for intraductal papillary mucinous neoplasms (IPMNs). A video demonstrates the technique in a patient with main duct-IPMN, highlighting its feasibility as a minimally invasive, organ-preserving alternative to pancreaticoduodenectomy.
07:17
An Orthotopic Resectional Mouse Model of Pancreatic Cancer
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Cited by 8 •
2020
In the clinical context, patients with localized pancreatic cancer will undergo pancreatectomy followed by adjuvant treatment. This protocol reported here aims to establish a safe and effective method of modelling this clinical scenario in nude mice, through orthotopic implantation of pancreatic cancer followed by distal pancreatectomy and splenectomy.
05:11
Treatment of Middle-segment Pancreatic Benign Tumor Using Laparoscopic Central Pancreatectomy with End-to-end Pancreatic Duct Reconstruction
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2026
This article presents laparoscopic central pancreatectomy with pancreatic duct end-to-end anastomosis as an important surgical approach for middle-segment pancreatic benign and low-grade malignant tumors.
03:58
Brain Tumor Resection in a Mouse Using a Minimally Invasive Resection System
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2025
Source: Alomari, S., et al. Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection. J. Vis. Exp. (2022)This video demonstrates the use of a minimally invasive resection system (MIRS) to excise tumor tissue from an anesthetized mouse implanted with a tumor. The procedure involves securing the mouse onto a stereotactic frame, reopening the previous surgical site to access the brain, and inserting a specialized cannula that utilizes suction and a...
09:25
Bioluminescent Orthotopic Model of Pancreatic Cancer Progression
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Cited by 34 •
2013
Improved understanding of pancreatic cancer biology is critically needed to enable the development of better therapeutic options to treat pancreatic cancer. To address this need, we demonstrate an orthotopic model of pancreatic cancer that permits non-invasive monitoring of cancer progression using in vivo bioluminescence imaging.
FAQs
Lesion location guides which pancreatic segment surgeons remove and how much uninvolved tissue they can preserve. Disease near adjacent digestive organs or major blood vessels may require extending the operation beyond the pancreas, followed by reconstruction or vascular control. This location-based planning aims to address the structural problem while limiting unnecessary loss of pancreatic tissue.
Preserving uninvolved pancreas matters because pancreatic resection can alter both endocrine and exocrine function. Endocrine effects concern blood-glucose regulation, whereas exocrine effects involve digestion. The extent of tissue removed therefore has consequences beyond local disease control, helping explain why surgeons balance adequate removal against preservation whenever the disease pattern permits.
When disease or the planned resection affects adjacent digestive organs, reconstruction may be needed to restore continuity of the digestive pathway. Nearby blood vessels may also require control during the operation. These additional components make the procedure more than a straightforward tissue removal and require operative planning that accounts for both local anatomy and safe management of surrounding structures.
Examination of the removed specimen provides two important assessments: the nature of the disease and the status of the surgical margins. Margin assessment helps characterize how the removed tissue relates to the disease at its edges. Together, these findings document the pathological result of the operation and contribute to judging disease control after surgery.
After surgery, care teams monitor digestion, blood glucose, leaks, and infection. These checks reflect the main consequences that can follow pancreatic resection: altered digestive or endocrine function and complications involving the operative site. Monitoring is therefore not limited to the incision; it also evaluates how the patient is adapting physiologically and whether complications require attention.
Management often must coordinate disease assessment, operative planning, reconstruction when needed, specimen interpretation, and postoperative monitoring. This coordination matters because treatment must address the underlying structural disease while also managing digestion, blood glucose, leaks, and infection. A multidisciplinary approach links the surgical decision with pathological assessment and recovery, rather than treating each stage as an isolated task.