Primary Intention

Primary intention is a form of wound healing in which clean, uninfected wound edges are closely approximated, typically with sutures, staples, or adhesive, to restore tissue continuity with minimal tissue loss. After closure, inflammation removes damaged material and limits contamination, while fibroblasts produce collagen and new tissue forms across the narrow wound gap; subsequent remodeling strengthens the repair and usually leaves a relatively small scar. In medicine, healing by primary intention is commonly used for surgical incisions and straightforward lacerations, where careful closure can shorten healing time, reduce scarring, and support predictable recovery.

Primary Intention - Related Videos

Education

JoVE Science Education - Psychology

Children's Reliance on Artist Intentions When Identifying Pictures

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2023

Source: Laboratories of Judith Danovitch and Nicholaus Noles—University of Louisville Children are not the best artists. Sometimes it’s easy to pick out the characteristic triangular head, whiskers, and tail of a cat, but children often describe elaborate scenarios that they depict as a beautifully unrecognizable mess. Thus, given children’s questionable artistic talent, how do they know what their drawings, and the drawings of others, represent? One way children identify pictures is by relying...

Research

JoVE Journal - Behavior

How Virtual Celebrity Characteristics Drive Purchase Intention: Testing the Stimulus-Organism-Response Framework with Structural Equation Modeling

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2026

In the context of the virtual celebrity experience, content quality most strongly drives satisfaction; satisfaction, in turn, increases purchase intention indirectly via loyalty. Personalization strengthens the satisfaction-loyalty link, so firms should prioritize emotion-evoking, narrative-consistent virtual celebrity content and personalized loyalty programs.

Research

JoVE Journal - Behavior
Free Sample

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

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Cited by 3 •

2015

This protocol presents a novel methodology for the neural decoding of intent from freely-behaving infants during unscripted social interaction with an actor. Neural activity is acquired using non-invasive high-density active scalp electroencephalography (EEG). Kinematic data is collected with inertial measurement units and supplemented with synchronized video recording.

Using Primary Neurosphere Cultures to Study Primary Cilia

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Cited by 3 •

2017

The primary cilium is fundamentally important in neural progenitor cell proliferation, neuronal differentiation, and adult neuronal function. Here, we describe a method to study ciliogenesis and the trafficking of signaling proteins to cilia in neural stem/progenitor cells and differentiated neurons using primary neurosphere cultures.

Primary Neuronal Cultures

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2023

The complexity of the brain often requires neuroscientists to use a simpler system for experimental manipulations and observations. One powerful approach is to generate a primary culture by dissecting nervous system tissue, dissociating it into single cells, and growing those cells in vitro. Primary cultures make neurons and glia easily accessible to the experimental tools required for techniques like genetic manipulation and time-lapse imaging. Furthermore, these cultures represent a highly...

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