Scalp Injection

Scalp injection is a medical technique that delivers medication or other therapeutic substances into selected layers of the scalp, enabling targeted treatment while limiting exposure to the rest of the body. Using sterile preparation and anatomical landmarks, a clinician guides a needle through the skin to deposit an agent intradermally, subcutaneously, or near deeper tissues, depending on the treatment goal. Applications include local anesthesia for procedures, corticosteroid treatment of inflammatory scalp disorders, and injection-based approaches for certain hair-loss conditions. Proper technique, dosing, and patient assessment help improve treatment precision while reducing complications such as pain, bleeding, infection, or tissue injury.

Scalp Injection - Related Videos

Research

JoVE Journal - Neuroscience

A Novel Scalp Acupuncture-based Method to Target the Hand Motor Hotspot for Non-invasive Brain Stimulation

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2025

This protocol introduces a scalp acupuncture-based method for localizing the primary motor cortex (M1) hotspot for the flexor digitorum superficialis (FDS) muscle and validates its effectiveness against the conventional C3 site.

Research

JoVE Journal - Behavior
Free Sample

Simultaneous Scalp Electroencephalography (EEG), Electromyography (EMG), and Whole-body Segmental Inertial Recording for Multi-modal Neural Decoding

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Cited by 28 •

2013

Development of an effective brain-machine-interface (BMI) system for restoration and rehabilitation of bipedal locomotion requires accurate decoding of user's intent. Here we present a novel experimental protocol and data collection technique for simultaneous non-invasive acquisition of neural activity, muscle activity, and whole-body kinematics during various locomotion tasks and conditions.

Establishing a Focal Demyelination Mouse Model via a Two-Point Injection of Lysophosphatidylcholine

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2025

This video demonstrates the generation of a focal demyelination mouse model using a two-point Lysophosphatidylcholine (LPC) injection. The skull of an anesthetized mouse is exposed. The injection coordinates are determined, and a hole is drilled to enable LPC injections at targeted sites. LPC induces focal demyelination of neurons via inflammation, while a two-point injection ensures its sustainability.

Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin

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2025

This video demonstrates a method to generate a rat model of neonatal intraventricular hemorrhage. In this procedure, an anesthetized rat pup is injected with hemoglobin into the lateral ventricle of the brain. The hemoglobin causes oxidative stress and releases heme, simulating intraventricular hemorrhage. The resulting damage to brain tissues, driven by reactive oxygen species and inflammatory cytokines, leads to ventricular enlargement, a common consequence of intraventricular hemorrhage.

Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice

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Cited by 28 •

2011

The autologous blood injection model of intracerebral hemorrhage in mice described in this protocol uses the double injection technique to minimize risk of blood reflux up the needle track, no anticoagulants in the pumping system, and eliminates all dead space and expandable tubing in the system.

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