Speech Coding Strategies

Speech coding strategies are methods for converting acoustic speech into a form that can be processed or delivered by medical hearing devices, particularly cochlear implants. They analyze features such as the speech signal’s frequency content and temporal envelope, then translate selected information into patterns of electrical stimulation across electrode channels; different strategies prioritize spectral detail, timing cues, or processing efficiency. In clinical medicine, these strategies guide device programming and rehabilitation for people with severe to profound hearing loss. Comparing their effects on speech perception, listening in noise, and user adaptation helps clinicians tailor treatment and supports improvements in auditory prostheses.

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Research

JoVE Journal - Behavior

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Cited by 41 •

2017

Ultrasound imaging can be used to display the shape and movements of the tongue in real time during speech. The images can be used to determine the nature of speech sound errors. Visual feedback of the tongue can be used to facilitate improvements in speech sound production in clinical populations.

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JoVE Core - Molecular Biology

lncRNA - Long Non-coding RNAs

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2020

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...

lncRNA - Long Non-coding RNAs

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2023

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA (lncRNA)...

Research

JoVE Journal - Genetics
Free Sample

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells

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Cited by 2 •

2025

This study presents a dual CRISPRi system targeting long non-coding RNAs in melanoma cells. It enables combinatorial gene knockdown and synthetic lethal screening, identifying cancer-specific lncRNA interactions for potential therapeutic strategies.

Identification of Coding and Non-coding RNA Classes Expressed in Swine Whole Blood

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2018

Here, we present a protocol optimized for the processing of coding (mRNA) and non-coding (ncRNA) globin reduced RNA-seq libraries from a single whole blood sample.

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