Ventral Onlay Graft
Ventral Onlay Graft - Related Videos
05:09
Urethral Stricture Induction Followed by Buccal Mucosa Graft Urethroplasty in a Rat Model
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Cited by 3 •
2023
In the present protocol, a urethral stricture induction was developed in Wistar rats, followed by urethral reconstruction with a buccal mucosa graft. A retrograde urethrogram and laser Doppler assessment were performed, validating urethral reconstruction (after stricture formation) and graft placement.
05:13
Co-culturing of Ventral Hippocampal and Nucleus Accumbens
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2025
This video demonstrates the process of preparing ventral hippocampal and nucleus accumbens tissues from mouse brains for co-culture. Neurons extend projections to form synaptic connections between the ventral hippocampal and nucleus accumbens tissues. This method allows studying neuronal interactions between these two brain regions, offering insights into cognition, behavior, and neurological disorders.
07:37
Mouse Models for Graft Arteriosclerosis
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Cited by 17 •
2013
We describe protocols for our mouse graft arteriosclerois (GA) models which involve interposition of a mouse vessel segment into a recipient of the same inbred strain. By backcrossing additional genetic changes into the vessel donor, the model can assess the effect of specific genes on GA.
09:19
In ovo Expression of MicroRNA in Ventral Chick Midbrain
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Cited by 5 •
2013
Ectopic expression is one technique to elucidate the microRNAs role in brain development. However, targeting specific areas using in ovo electroporation is challenging. Here, we show an efficient way to selectively electroporate ventral and dorsal midbrain regions.
05:47
Use of a Rat Model to Study Ventral Abdominal Hernia Repair
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Cited by 5 •
2017
This manuscript describes methods associated with creation and repair of a ventral abdominal wall defect (hernia). This model can be used to study repair strategies such as those that use implanted materials. In this manuscript, repair of the experimental hernia with porcine small intestinal submucosa is presented as an example.
FAQs
Preserving the existing urethral plate allows reconstruction to add tissue without removing the entire narrowed segment. The graft enlarges the ventral portion of the lumen while the native plate remains part of the repair. This combination supports restoration of urine flow and helps create a stable reconstructed channel after healing.
Excision and primary repair may not suit strictures that are long or dense. In those situations, removing the narrowed segment and joining the ends directly may be less appropriate than augmenting the existing urethral plate. A ventral onlay graft provides a way to widen the affected area while retaining native urethral tissue.
Graft integration determines whether the added tissue becomes a durable part of the widened urethral wall. The graft must heal onto the exposed corporal tissue and remain incorporated as the repair matures. Appropriate patient selection, successful integration, and satisfactory healing therefore influence whether the reconstruction maintains a stable lumen and improved urine passage.
The surgeon exposes the narrowed urethral segment and opens it along the length of the stricture. A graft, commonly buccal mucosa, is placed against the exposed corporal tissue, and its edges are sutured to the urethral margins. This arrangement enlarges the ventral wall while preserving the existing urethral plate.
The technique is particularly relevant to anterior urethral stricture disease involving long or dense bulbar strictures. These patterns may be unsuitable for simple excision and primary repair, making augmentation of the ventral wall a useful reconstructive option. The decision still depends on selecting patients whose anatomy and healing prospects support graft-based reconstruction.
The intended outcomes are a larger, stable urethral lumen and improved urine flow through the previously narrowed segment. In medical practice, the technique addresses structural obstruction rather than merely relieving symptoms temporarily. Its effectiveness depends on how well the graft incorporates and heals within the reconstruction, as well as on appropriate patient selection.