Cortical Implantation
Cortical Implantation - Related Videos
04:00
Subdural Implantation of a Soft Electrocorticography Array for Cortical Electrophysiology Recording in Minipigs
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2025
This video demonstrates the implantation of a soft electrocorticography array and the long-term cortical recordings in a minipig. It outlines the steps involved in surgically implanting the array over the minipig's auditory cortex and recording both baseline and sound stimulus-evoked neuronal action potentials.
04:43
Chronic Implantation of Whole-cortical Electrocorticographic Array in the Common Marmoset
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Cited by 16 •
2019
We have developed a whole-cortical electrocorticographic array for the common marmoset that continuously covers almost the entire lateral surface of cortex, from the occipital pole to the temporal and frontal poles. This protocol describes a chronic implantation procedure of the array in the epidural space of the marmoset brain.
08:30
Subdural Soft Electrocorticography (ECoG) Array Implantation and Long-Term Cortical Recording in Minipigs
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Cited by 6 •
2023
Here, we present a method for the long-term performance and safety assessment of soft subdural electrode arrays in a minipig model, describing surgical method and tools, postoperative magnetic resonance imaging, electrophysiology of the auditory cortex, electrochemical properties of the implant, and postmortem immunochemistry.
03:49
Recording Cortical and Subcortical Neuronal Activity Using Electrode Systems
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2025
This video demonstrates the process of recording cortical and subcortical neuronal activity using electroencephalography (EEG) and deep brain stimulation (DBS) electrodes during an attention-based visual stimulation test.
11:25
Isolation and Culture of Mouse Cortical Astrocytes
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Cited by 460 •
2013
Astrocytes have been recognized to be versatile cells participating in fundamental biological processes that are essential for normal brain development and function, and central nervous system repair. Here we present a rapid procedure to obtain pure mouse astrocyte cultures to study the biology of this major class of central nervous system cells.
FAQs
Recording systems detect electrical signals generated by cortical neurons, allowing researchers to examine ongoing neural activity. Stimulation systems work in the opposite direction by delivering controlled currents to selected cortical regions. Using one or both functions lets investigators compare naturally occurring activity with responses produced by targeted stimulation, supporting studies of brain function and the development of neural interfaces.
Placement determines which cortical activity a device can access and which region can receive stimulation. Devices positioned on the cortex provide access at its surface, whereas devices placed within the cortex interface more directly with tissue in that region. Matching placement to the cortical area of interest helps align recordings or stimulation with a study’s neural target.
Implanted sensors provide neural signals that can be recorded and then interpreted as patterns related to brain activity. Those interpreted signals may be translated into commands or other assistive outputs, creating a foundation for brain-computer interfaces and neuroprosthetic technologies. The central research challenge is connecting cortical activity with useful therapeutic or assistive outcomes.
Monitoring supplies information about electrical activity produced by cortical neurons, while targeted stimulation tests how selected regions respond when controlled currents are delivered. Together, these functions provide complementary evidence: recording shows neural activity as it occurs, and stimulation allows investigators to examine the effects of activating particular cortical areas. This combination broadens experimental access to brain function.
A craniotomy or burr hole first provides physical access to the brain. Electrodes or another device are then placed on or within the cerebral cortex, depending on the intended interface. Sensors can be used to detect cortical electrical signals, while a stimulation system may deliver controlled currents to selected regions. These steps establish the recording or stimulation interface.
Researchers use this approach when direct access to cortical activity is needed for studying brain function, epilepsy, motor control, or sensory processing. It is also relevant when experiments require controlled stimulation or neural signals that can be interpreted for an interface. The method therefore connects basic investigations of cortical activity with therapeutic and assistive technology development.
By detecting electrical signals from the cortex, implanted sensors can support investigations of how neural activity relates to brain function and epilepsy. The resulting recordings provide a direct basis for examining activity in cortical regions of interest. When stimulation is included, researchers can also study the effects of controlled currents on selected areas, adding a functional dimension to the investigation.