Left Dorsolateral Prefrontal Cortex
Left Dorsolateral Prefrontal Cortex - Related Videos
04:31
Combined Transcranial Magnetic Stimulation and Electroencephalography of the Dorsolateral Prefrontal Cortex
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2025
Source: Lioumis, P. et al. Combined Transcranial Magnetic Stimulation and Electroencephalography of the Dorsolateral Prefrontal Cortex. J. Vis. Exp. (2018)This video demonstrates a protocol for combining transcranial magnetic stimulation and electroencephalography to assess cortical excitability and the balance between excitation and inhibition in the dorsolateral prefrontal cortex.
07:42
Combined Transcranial Magnetic Stimulation and Electroencephalography of the Dorsolateral Prefrontal Cortex
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Cited by 13 •
2018
The protocol presented here is for TMS-EEG studies utilizing intracortical excitability test-retest design paradigms. The intent of the protocol is to produce reliable and reproducible cortical excitability measures for assessing neurophysiological functioning related to therapeutic interventions in the treatment of neuropsychiatric diseases such as major depression.
13:20
Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance
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2025
This protocol presents a more precise and effective method of repetitive transcranial magnetic stimulation of the dorsolateral and dorsomedial prefrontal cortices during an experimental task using neuronavigation and robotic systems. Based on the results, crucial implications are suggested for future online stimulation research.
06:11
High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity
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Cited by 1 •
2025
This study proposed an experimental paradigm that applies High-Definition Transcranial Direct Current Stimulation (HD-tDCS) to improve human metacognition in human-AI delegation tasks. The results demonstrated the effectiveness of HD-tDCS in enhancing metacognitive sensitivity.
03:59
MRI-Guided Repetitive Transcranial Magnetic Stimulation to the Dorsomedial Prefrontal Cortex
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2025
Source: Dunlop, K., et al. MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder. J. Vis. Exp. (2015)This video demonstrates the procedure for MRI-guided repetitive transcranial magnetic stimulation (rTMS) targeting the dorsomedial prefrontal cortex (dmPFC) to treat depression.
FAQs
Executive control depends on coordination rather than isolated activity within the left dorsolateral prefrontal cortex. Its interactions with other prefrontal, parietal, and subcortical regions help maintain information relevant to a task and regulate responses. This network-level organization supports goal-directed behavior by linking current task demands with controlled actions.
The left DLPFC contributes to cognitive flexibility by helping the brain adjust behavior as goals or task requirements shift. Its involvement in attention, planning, working memory, and cognitive control allows relevant information to remain available while responses are regulated. These functions help organize behavior around changing objectives rather than immediate or automatic reactions.
Research examines the left DLPFC in language-related processing because executive control can help organize how information is selected, maintained, and used during complex tasks. Studying this region alongside its broader roles in attention and working memory helps neuroscience investigate how language-related operations interact with general systems for controlled, goal-directed behavior.
Three approaches identified in this research area are functional neuroimaging, lesion analysis, and noninvasive brain stimulation. Functional neuroimaging examines activity, lesion analysis relates changes in the region to behavior, and stimulation tests the effects of altering activity without surgery. Together, these methods provide complementary ways to study the region's contribution to complex behavior.
Studies examine the left DLPFC in decision-making, language-related processing, emotion regulation, and cognitive flexibility. These applications extend beyond any single executive function because they test how controlled attention, maintained information, planning, and response regulation contribute to different forms of behavior. Comparing these domains helps clarify the region's broader role in organizing complex mental activity.
Altered prefrontal activity is relevant because researchers use the left DLPFC to investigate how changes in brain organization may relate to neurological and psychiatric conditions. The region offers a way to connect differences in executive control, decision-making, emotion regulation, or cognitive flexibility with broader changes in complex behavior, helping explain how brain activity relates to symptoms and function.