Platinum Carbon Coating

Platinum carbon coating is an electron-microscopy sample-preparation method that deposits a thin, conductive layer of platinum and carbon onto a specimen or support, improving image quality by limiting surface charging. Under vacuum, platinum and carbon are vaporized and deposited as a fine film; the metal enhances electrical conductivity and surface contrast, while the carbon matrix helps stabilize the coating for imaging. In neuroscience, this approach supports high-resolution examination of neuronal membranes, synapses, axonal structures, and other cellular features by scanning or transmission electron microscopy. Reliable coating can improve signal stability, reveal ultrastructural organization, and aid quantitative analysis of neural tissue.

Platinum Carbon Coating - Related Videos

Research

JoVE Journal - Chemistry

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

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Cited by 1 •

2014

This protocol describes the use of amide coupling reactions of isonicotinic acid and diaminoalkanes to form bridging ligands suitable for use in the synthesis of multinuclear platinum complexes, which combine aspects of the anticancer drugs BBR3464 and picoplatin.

Graphene Coatings for Biomedical Implants

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Cited by 37 •

2013

Graphene offers potential as a coating material for biomedical implants. In this study we demonstrate a method for coating nitinol alloys with nanometer thick layers of graphene and determine how graphene may influence implant response.

Education

JoVE Core - Biology

The Carbon Cycle

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2019

Carbon is the basis of all organic matter on Earth, and is recycled through the ecosystem in two primary processes: one in which carbon is exchanged among living organisms, and one in which carbon is cycled over long periods of time through fossilized organic remains, weathering of rocks, and volcanic activity. Human activities, including increased agricultural practices and the burning of fossil fuels, has greatly affected the balance of the natural carbon cycle. Biological Carbon Cycle All...

Preparation of Carbon Nanosheets at Room Temperature

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2016

We present the synthesis of an amphiphilic hexayne and its use in the preparation of carbon nanosheets at the air-water interface from a self-assembled monolayer of these reactive, carbon-rich molecular precursors.

Fabrication of 3D Carbon Microelectromechanical Systems (C-MEMS)

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Cited by 6 •

2017

Long and hollow glassy carbon microfibers were fabricated based on the pyrolysis of a natural product, human hair. The two fabrication steps of carbon microelectromechanical and carbon nanoelectromechanical systems, or C-MEMS and C-NEMS, are: (i) photolithography of a carbon-rich polymer precursor and (ii) pyrolysis of the patterned polymer precursor.

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