Primary Visual Cortex

Primary visual cortex (V1) is the first cortical stage of visual processing, receiving information from the eyes through the lateral geniculate nucleus and transforming it into neural representations of the visual scene. Within V1, retinotopic organization preserves neighboring relationships from the retina, while layered circuits and selective neurons analyze features such as orientation, spatial frequency, and contrast. In neuroscience, studying V1 with electrophysiology, neuroimaging, lesions, and computational models helps explain how sensory signals become perception, guides research on visual disorders, and provides a foundation for understanding cortical plasticity and brain-machine interfaces.

Primary Visual Cortex - Related Videos

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JoVE Journal - Developmental Biology

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex

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Cited by 1 •

2020

Here, we present detailed protocols for monocular visual deprivation and ocular dominance plasticity analysis, which are important methods for studying the neural mechanisms of visual plasticity during the critical period and the effects of specific genes on visual development.

Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention

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Cited by 21 •

2017

Using two different transcranial magnetic stimulation (TMS) protocols, this manuscript describes how to measure and compare cortical inhibition within the primary motor cortex when adopting different attentional foci.

Time-Lapse Imaging of Transfected Primary Mouse Cerebral Cortex Cells

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2025

Source: Landeira, B. S.,et al., Live Imaging of Primary Cerebral Cortex Cells Using a 2D Culture System. J. Vis. Exp. (2017)The video demonstrates the use of time-lapse imaging to track fluorescently labeled cortical progenitors, monitor their division and differentiation, and study lineage development in primary cerebral cortex...

Chronic Imaging of Mouse Visual Cortex Using a Thinned-skull Preparation

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Cited by 20 •

2010

In this video and supplemental material, we show a protocol for chronic in vivo imaging of the intact brain using a thinned-skull preparation.

Live Imaging of Primary Cerebral Cortex Cells Using a 2D Culture System

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Cited by 2 •

2017

Live imaging is a powerful tool to study cellular behaviors in real time. Here, we describe a protocol for time-lapse video-microscopy of primary cerebral cortex cells that allows a detailed examination of the phases enacted during the lineage progression from primary neural stem cells to differentiated neurons and glia.

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