/
/
Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
A subscription to JoVE is required to view this content. Sign in or start your free trial.
1The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for NeuroInformation,University of Electronic Science and Technology of China, 2Sichuan Institute for Brain Science and Brain-inspired Intelligence, 3Department of Electronic Engineering,City University of Hong Kong, 4Centre for Biosystems, Neuroscience, and Nanotechnology,City University of Hong Kong
Chapters
- 00:00Introduction
- 00:59Monocular Deprivation at Postnatal Day 28 in Mice
- 03:21Craniotomy in the Mouse V1 Binocular Region after Monocular Deprivation on the 4th Day
- 05:25Visual Stimulation and Electrophysiological Recording
- 06:19Off-line Spike Sorting and Data Analysis
- 07:44Results
- 08:12Conclusion
Here, we present detailed protocols for monocular visual deprivation and ocular dominance plasticity analysis, which are important methods for studying the neural mechanisms of visual plasticity during the critical period and the effects of specific genes on visual development.
