Fixation Cross
Fixation Cross - Related Videos
10:21
Protocol for HER2 FISH Using a Non-cross-linking, Formalin-free Tissue Fixative to Combine Advantages of Cryo-preservation and Formalin Fixation
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Cited by 3 •
2017
Fluorescence in-situ hybridization (FISH) is often required in combination with histopathology and molecular diagnostics for selection of therapy in personalized medicine. A novel non-cross-linking, formalin-free tissue fixative that allows high quality morphologic, molecular and FISH analyses from the same specimen by addition of a post-fixation step before FISH is presented.
08:53
Whole Animal Perfusion Fixation for Rodents
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Cited by 531 •
2012
Here we describe a low-cost, rapid, controlled and uniform fixation procedure using 4% paraformaldehyde perfused via the vascular system: through the heart of the rat to obtain the best possible preservation of the brain.
01:03
Fixation and Sectioning
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2023
Two basic types of preparation are used to visualize specimens with a light microscope: wet mounts and fixed specimens. The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...
08:45
Genetic Crosses
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2023
To dissect genetic processes or create organisms with novel suites of traits, scientists can perform genetic crosses, or the purposeful mating of two organisms. The recombination of parental genetic material in the offspring allows researchers to deduce the functions, interactions, and locations of genes. This video will examine how genetic crosses were influential in developing Mendel's three laws of inheritance, which form the basis of our understanding of genetics. One genetic crossing...
08:55
Making a Geologic Cross Section
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2023
Source: Laboratory of Alan Lester - University of Colorado Boulder Geologic maps were first made and utilized in Europe, in the mid-to-late 18th century. Ever since, they have been an important part of geological investigations all around the world that strive to understand rock distributions on the surface of the earth, in the subsurface, and their modification through time. A modern geologic map is a data-rich representation of rocks and rock-structures in a two-dimensional plan view. The...
FAQs
Its main value is standardization: each trial begins after participants have been asked to orient to the same display location. This reduces variation caused by different starting gaze positions or inconsistent preparation, making differences in reaction time, eye movements, or brain activity easier to attribute to the stimulus or task. The result is more consistent comparison across trials.
The marker provides a common visual starting point before the target appears. When participants begin from a more consistent gaze position, the recorded response is less affected by where they were looking immediately beforehand. This can improve interpretation of reaction times and eye movements by reducing unwanted trial-to-trial variation unrelated to the experimental stimulus.
Looking at the cross gives participants a clear preparatory event before the task-relevant display. It helps organize when attention should be directed toward the upcoming trial and supports a more consistent transition from preparation to stimulus processing. This is especially relevant when researchers compare attentional responses across perception, memory, or decision-making conditions.
A typical trial asks the participant to look at the cross before presenting the experimental stimulus. The stimulus then appears after this common preparation stage, followed by the participant’s task response or measured behavior. Repeating that sequence across trials helps align gaze position, attentional preparation, and trial timing for subsequent analysis.
They are useful when researchers need measurements to begin from a more consistent visual and attentional state. In eye-tracking, this supports comparison of gaze behavior across trials. In neuroimaging, the common preparation stage helps organize the timing of stimulus-related brain-activity measurements. In both settings, consistent setup can strengthen interpretation of recorded responses.
The technique supports studies of attention, memory, and decision-making in addition to perception. It can precede different task stimuli while preserving a consistent starting procedure, allowing researchers to compare behavioral or physiological responses across experimental conditions. Its broader value lies in reducing irrelevant variation while examining how participants process information and make responses.