Daniel Irimia

The BioMEMS Resource Center, Massachusetts General Hospital

Affiliated withMassachusetts General Hospital Harvard Medical School Shriners Burns Hospital

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 20	2014
Publication title Cited by 8	2017

Other Publications

Article	Year
Neutrophil migration assay from a drop of blood. Lab on a chip\| PubMed ID: 19023468	2008
Kinetics and mechanism of intercellular ice propagation in a micropatterned tissue construct. Biophysical journal\| PubMed ID: 11916845	2002
Parametric analysis of intercellular ice propagation during cryosurgery, simulated using monte carlo techniques. Technology in cancer research & treatment\| PubMed ID: 15059017	2004
Kinetics of intracellular ice formation in one-dimensional arrays of interacting biological cells. Biophysical journal\| PubMed ID: 15475590	2005
Single-cell chemical lysis in picoliter-scale closed volumes using a microfabricated device. Analytical chemistry\| PubMed ID: 15481964	2004
Blood-on-a-chip. Annual review of biomedical engineering\| PubMed ID: 16004567	2005
Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients. Lab on a chip\| PubMed ID: 16450027	2006
Murine B16 melanomas expressing high levels of the chemokine stromal-derived factor-1/CXCL12 induce tumor-specific T cell chemorepulsion and escape from immune control. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16493048	2006
Cell handling using microstructured membranes. Lab on a chip\| PubMed ID: 16511616	2006
Universal microfluidic gradient generator. Analytical chemistry\| PubMed ID: 16689552	2006
A high-throughput microfluidic real-time gene expression living cell array. Lab on a chip\| PubMed ID: 17180208	2007
A microfluidic device for practical label-free CD4(+) T cell counting of HIV-infected subjects. Lab on a chip\| PubMed ID: 17268618	2007
A microchip approach for practical label-free CD4+ T-cell counting of HIV-infected subjects in resource-poor settings. Journal of acquired immune deficiency syndromes (1999)\| PubMed ID: 17414933	2007
Cell detection and counting through cell lysate impedance spectroscopy in microfluidic devices. Lab on a chip\| PubMed ID: 17538717	2007
Continuous inertial focusing, ordering, and separation of particles in microchannels. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18025477	2007
Polar stimulation and constrained cell migration in microfluidic channels. Lab on a chip\| PubMed ID: 18030401	2007
A microfluidic bioreactor for increased active retrovirus output. Lab on a chip\| PubMed ID: 18094764	2008
Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature\| PubMed ID: 18097410	2007
Equilibrium separation and filtration of particles using differential inertial focusing. Analytical chemistry\| PubMed ID: 18275222	2008
Synthetic microvascular networks for quantitative analysis of particle adhesion. Biomedical microdevices\| PubMed ID: 18327641	2008
Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients. Clinical chemistry\| PubMed ID: 18375483	2008
Elastomeric microchip electrospray emitter for stable cone-jet mode operation in the nanoflow regime. Analytical chemistry\| PubMed ID: 18419138	2008
Cell-cell interaction modulates neuroectodermal specification of embryonic stem cells. Neuroscience letters\| PubMed ID: 18467031	2008
'Living cantilever arrays' for characterization of mass of single live cells in fluids. Lab on a chip\| PubMed ID: 18584076	2008
Detection of mutations in EGFR in circulating lung-cancer cells. The New England journal of medicine\| PubMed ID: 18596266	2008
Controlled encapsulation of single-cells into monodisperse picolitre drops. Lab on a chip\| PubMed ID: 18651066	2008
TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton. Journal of cell science\| PubMed ID: 18827015	2008
Microvortex for focusing, guiding and sorting of particles. Lab on a chip\| PubMed ID: 19023476	2008
Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19050288	2008
In situ characterization of a cold and short pulsed molecular beam by femtosecond ion imaging. Physical chemistry chemical physics : PCCP\| PubMed ID: 19440625	2009
Adaptive-control model for neutrophil orientation in the direction of chemical gradients. Biophysical journal\| PubMed ID: 19450463	2009
Nucleation and solidification in static arrays of monodisperse drops. Lab on a chip\| PubMed ID: 19532960	2009
Chemical gradient-mediated melting curve analysis for genotyping of SNPs. Electrophoresis\| PubMed ID: 19593749	2009
Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport. Journal of neurochemistry\| PubMed ID: 19686388	2009
Cutting edge: electronic counting of white blood cells. Lab on a chip\| PubMed ID: 19789737	2009
Coherent oscillatory femtosecond dynamics in multichannel photodynamics of NO2 studied by spatially masked electron imaging. The journal of physical chemistry. A\| PubMed ID: 19928822	2010
A short pulse (7 micros FWHM) and high repetition rate (dc-5 kHz) cantilever piezovalve for pulsed atomic and molecular beams. The Review of scientific instruments\| PubMed ID: 19947724	2009
Spontaneous migration of cancer cells under conditions of mechanical confinement. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 20023765	2009
Genome-wide transcriptome analysis of 150 cell samples. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 20023796	2009
Microfluidic isolation and transcriptome analysis of serum microvesicles. Lab on a chip\| PubMed ID: 20126692	2010
MYC regulation of a "poor-prognosis" metastatic cancer cell state. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20133671	2010
Microfluidic technologies for temporal perturbations of chemotaxis. Annual review of biomedical engineering\| PubMed ID: 20450351	2010
Toward elucidating the mechanism of femtosecond pulse shaping control in photodynamics of molecules by velocity map photoelectron and ion imaging. The Journal of chemical physics\| PubMed ID: 20572700	2010
Controlled induction of distributed microdeformation in wounded tissue via a microchamber array dressing. Journal of biomedical materials research. Part A\| PubMed ID: 20607869	2010
Directional decisions during neutrophil chemotaxis inside bifurcating channels. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 20676444	2010
Burn injury reduces neutrophil directional migration speed in microfluidic devices. PloS one\| PubMed ID: 20689600	2010
Clinical microfluidics for neutrophil genomics and proteomics. Nature medicine\| PubMed ID: 20802500	2010
Isolation of circulating tumor cells using a microvortex-generating herringbone-chip. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20930119	2010
A genome-wide RNAi screen identifies multiple RSK-dependent regulators of cell migration. Genes & development\| PubMed ID: 21062900	2010
Ultrasensitive detection of low-abundance surface-marker protein using isothermal rolling circle amplification in a microfluidic nanoliter platform. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 21294269	2011
Microfluidics for T- lymphocyte cell separation and inflammation monitoring in burn patients. Clinical and translational science\| PubMed ID: 21348958	2011
The reaction microscope: imaging and pulse shaping control in photodynamics. Chemphyschem : a European journal of chemical physics and physical chemistry\| PubMed ID: 21506237	2011
Subsets of human CD4(+) regulatory T cells express the peripheral homing receptor CXCR3. European journal of immunology\| PubMed ID: 21538345	2011
The Reaction Microscope: Imaging and Pulse Shaping Control in Photodynamics. Chemphyschem : a European journal of chemical physics and physical chemistry\| PubMed ID: 21557438	2011
Decoding functional metabolomics with docosahexaenoyl ethanolamide (DHEA) identifies novel bioactive signals. The Journal of biological chemistry\| PubMed ID: 21757729	2011
Microfluidic proportional flow controller. Journal of micromechanics and microengineering : structures, devices, and systems\| PubMed ID: 21874096	2010
Controlled loading of cryoprotectants (CPAs) to oocyte with linear and complex CPA profiles on a microfluidic platform. Lab on a chip\| PubMed ID: 21887438	2011
On a chip. IEEE pulse\| PubMed ID: 22147065	2011
Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility. Science (New York, N.Y.)\| PubMed ID: 22174129	2012
Epithelial cell guidance by self-generated EGF gradients. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 22314635	2012
Resolvin E2 formation and impact in inflammation resolution. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22450811	2012
Photoelectron photoion coincidence imaging of ultrafast control in multichannel molecular dynamics. Faraday discussions\| PubMed ID: 22452081	2011
Multiple phenotypes in Huntington disease mouse neural stem cells. Molecular and cellular neurosciences\| PubMed ID: 22508027	2012
A portable chemotaxis platform for short and long term analysis. PloS one\| PubMed ID: 23028729	2012
Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23033492	2012
Resolvin D2 prevents secondary thrombosis and necrosis in a mouse burn wound model. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society\| PubMed ID: 23110665	2013
Microfluidic chambers for monitoring leukocyte trafficking and humanized nano-proresolving medicines interactions. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23185003	2012
Resolvin D2 restores neutrophil directionality and improves survival after burns. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 23430978	2013
Mitochondrial localization and the persistent migration of epithelial cancer cells. Biophysical journal\| PubMed ID: 23663851	2013
Microfluidic chemotaxis platform for differentiating the roles of soluble and bound amyloid-β on microglial accumulation. Scientific reports\| PubMed ID: 23665843	2013
Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell host & microbe\| PubMed ID: 23684304	2013
MICROFLUIDIC DEVICE FOR EXAMINING DIRECTIONAL SENSING IN DENDRITIC CELL CHEMOTAXIS. Nano LIFE\| PubMed ID: 24073020	2012
Desiccation kinetics of biopreservation solutions in microchannels. Journal of applied physics\| PubMed ID: 24155501	2006
Biased migration of confined neutrophil-like cells in asymmetric hydraulic environments. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24324148	2013
Retrotaxis of human neutrophils during mechanical confinement inside microfluidic channels. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 24419464	2014
On-demand, competing gradient arrays for neutrophil chemotaxis. Lab on a chip\| PubMed ID: 24430002	2014
Migration of neutrophils targeting amyloid plaques in Alzheimer's disease mouse model. Neurobiology of aging\| PubMed ID: 24485508	2014
Cell migration in confined environments. Methods in cell biology\| PubMed ID: 24560508	2014
A zebrafish compound screen reveals modulation of neutrophil reverse migration as an anti-inflammatory mechanism. Science translational medicine\| PubMed ID: 24574340	2014
Measuring neutrophil speed and directionality during chemotaxis, directly from a droplet of whole blood. Technology\| PubMed ID: 24809064	2013
Microfluidic platform to evaluate migration of cells from patients with DYT1 dystonia. Journal of neuroscience methods\| PubMed ID: 24880044	2014
Technical Advance: Changes in neutrophil migration patterns upon contact with platelets in a microfluidic assay. Journal of leukocyte biology\| PubMed ID: 27630219	2017