Arthur E. Warrington

Department of Neurology, Mayo Clinic College of Medicine

Affiliated withMayo Clinic College of Medicine Mayo Clinic

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 1	2014
Publication title Cited by 2	2016

Other Publications

Article	Year
Direct evidence that a human antibody derived from patient serum can promote myelin repair in a mouse model of chronic-progressive demyelinating disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12154009	2002
Remyelination-promoting antibodies activate distinct Ca2+ influx pathways in astrocytes and oligodendrocytes: relationship to the mechanism of myelin repair. Molecular and cellular neurosciences\| PubMed ID: 12595235	2003
Human monoclonal IgM antibody promotes CNS myelin repair independent of Fc function. Brain pathology (Zurich, Switzerland)\| PubMed ID: 14655764	2003
Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody. Neurobiology of disease\| PubMed ID: 14751777	2004
Neuron-binding human monoclonal antibodies support central nervous system neurite extension. Journal of neuropathology and experimental neurology\| PubMed ID: 15198125	2004
A human antibody that promotes remyelination enters the CNS and decreases lesion load as detected by T2-weighted spinal cord MRI in a virus-induced murine model of MS. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15319372	2004
STAT4- and STAT6-signaling molecules in a murine model of multiple sclerosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 16352646	2006
A recombinant human IgM promotes myelin repair after a single, very low dose. Journal of neuroscience research\| PubMed ID: 17304578	2007
Invited article: human natural autoantibodies in the treatment of neurologic disease. Neurology\| PubMed ID: 19349608	2009
Surface plasmon resonance for high-throughput ligand screening of membrane-bound proteins. Biotechnology journal\| PubMed ID: 19918786	2009
Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference\| PubMed ID: 19963504	2009
Cellular mechanisms of central nervous system repair by natural autoreactive monoclonal antibodies. Archives of neurology\| PubMed ID: 20008649	2009
Importance of oligodendrocyte protection, BBB breakdown and inflammation for remyelination. Expert review of neurotherapeutics\| PubMed ID: 20187865	2010
Method of identifying natural antibodies for remyelination. Journal of clinical immunology\| PubMed ID: 20387101	2010
The relevance of animal models in multiple sclerosis research. Pathophysiology : the official journal of the International Society for Pathophysiology / ISP\| PubMed ID: 20537877	2011
Autoantibodies with enzymatic properties in human autoimmune diseases. Journal of autoimmunity\| PubMed ID: 21624820	2011
Enhancing CNS repair in neurological disease: challenges arising from neurodegeneration and rewiring of the network. CNS drugs\| PubMed ID: 21699269	2011
A human IgM signals axon outgrowth: coupling lipid raft to microtubules. Journal of neurochemistry\| PubMed ID: 21824142	2011
Facile assembly of micro- and nanoarrays for sensing with natural cell membranes. ACS nano\| PubMed ID: 21842844	2011
Evidence for the role of B cells and immunoglobulins in the pathogenesis of multiple sclerosis. Neurology research international\| PubMed ID: 21961063	2011
A single dose of neuron-binding human monoclonal antibody improves spontaneous activity in a murine model of demyelination. PloS one\| PubMed ID: 22022490	2011
Need for a paradigm shift in therapeutic approaches to CNS injury. Expert review of neurotherapeutics\| PubMed ID: 22449213	2012
Remyelination induced by a DNA aptamer in a mouse model of multiple sclerosis. PloS one\| PubMed ID: 22761835	2012
High-affinity binding of remyelinating natural autoantibodies to myelin-mimicking lipid bilayers revealed by nanohole surface plasmon resonance. Analytical chemistry\| PubMed ID: 22762372	2012
Naturally occurring antibodies as therapeutics for neurologic disease: can human monoclonal IgMs replace the limited resource IVIG? Advances in experimental medicine and biology\| PubMed ID: 22903665	2012
Therapeutics to promote CNS repair: a natural human neuron-binding IgM regulates membrane-raft dynamics and improves motility in a mouse model of multiple sclerosis. Journal of clinical immunology\| PubMed ID: 22990667	2013
PDGF is required for remyelination-promoting IgM stimulation of oligodendrocyte progenitor cell proliferation. PloS one\| PubMed ID: 23383310	2013
A patterned recombinant human IgM guides neurite outgrowth of CNS neurons. Scientific reports\| PubMed ID: 23881231	2013
Cellular targets and mechanistic strategies of remyelination-promoting IgMs as part of the naturally occurring autoantibody repertoire. Expert review of neurotherapeutics\| PubMed ID: 24053345	2013
Applications of SPR for the characterization of molecules important in the pathogenesis and treatment of neurodegenerative diseases. Expert review of neurotherapeutics\| PubMed ID: 24625008	2014
Quantitative PCR analysis of DNA aptamer pharmacokinetics in mice. Nucleic acid therapeutics\| PubMed ID: 25536292	2015
Polysialic acid as an antigen for monoclonal antibody HIgM12 to treat multiple sclerosis and other neurodegenerative disorders. Journal of neurochemistry\| PubMed ID: 25866077	2015
A single dose of a neuron-binding human monoclonal antibody improves brainstem NAA concentrations, a biomarker for density of spinal cord axons, in a model of progressive multiple sclerosis. Journal of neuroinflammation\| PubMed ID: 25924771	2015
A natural human IgM that binds to gangliosides is therapeutic in murine models of amyotrophic lateral sclerosis. Disease models & mechanisms\| PubMed ID: 26035393	2015
Naturally Occurring Monoclonal Antibodies and Their Therapeutic Potential for Neurologic Diseases. JAMA neurology\| PubMed ID: 26389734	2015
Antibody-Mediated Oligodendrocyte Remyelination Promotes Axon Health in Progressive Demyelinating Disease. Molecular neurobiology\| PubMed ID: 26409478	2015
Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity. PLoS pathogens\| PubMed ID: 26633895	2015
Recent Advances in Monoclonal Antibody Therapies for Multiple Sclerosis. Expert opinion on biological therapy\| PubMed ID: 26914737	2016
A monoclonal natural human IgM protects axons in the absence of remyelination. Journal of neuroinflammation\| PubMed ID: 27126523	2016