Ronald C. Conaway

Stowers Institute for Medical Research

Affiliated withStowers Institute for Medical Research Kansas University Medical Center

Research Area

Biography

Ronald C. Conaway has not added Biography.
If you are Ronald C. Conaway and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 8	2014
Publication title Cited by 4	2014
Publication title Cited by 1	2019

Other Publications

Article	Year
MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression. The Journal of biological chemistry\| PubMed ID: 19049968	2009
Roles of SCF and VHL ubiquitin ligases in regulation of cell growth. Progress in molecular and subcellular biology\| PubMed ID: 11908068	2002
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature\| PubMed ID: 11961546	2002
Emerging roles of ubiquitin in transcription regulation. Science (New York, N.Y.)\| PubMed ID: 12016299	2002
A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase. The Journal of biological chemistry\| PubMed ID: 12048197	2002
Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12149480	2002
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12351678	2002
The von Hippel-Lindau tumor suppressor complex and regulation of hypoxia-inducible transcription. Advances in cancer research\| PubMed ID: 12374282	2002
Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex. The Journal of biological chemistry\| PubMed ID: 12538644	2003
Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3. The Journal of biological chemistry\| PubMed ID: 12584197	2003
von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12604794	2003
The RNA polymerase II elongation complex. Annual review of biochemistry\| PubMed ID: 12676794	2003
TFIIS and GreB: two like-minded transcription elongation factors with sticky fingers. Cell\| PubMed ID: 12914690	2003
Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex. The Journal of biological chemistry\| PubMed ID: 12963728	2003
A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex. The Journal of biological chemistry\| PubMed ID: 14576168	2003
A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2. The Journal of biological chemistry\| PubMed ID: 14638676	2004
Assays for investigating the mechanism of promoter escape by RNA polymerase II. Methods in enzymology\| PubMed ID: 14712687	2003
Preparation and assay of RNA polymerase II elongation factors elongin and ELL. Methods in enzymology\| PubMed ID: 14712707	2003
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular cell\| PubMed ID: 15175151	2004
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Molecular cell\| PubMed ID: 15175163	2004
Identification of Elongin C and Skp1 sequences that determine Cullin selection. The Journal of biological chemistry\| PubMed ID: 15280393	2004
Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53. Molecular and cellular biology\| PubMed ID: 15485928	2004
In vivo requirement of the RNA polymerase II elongation factor elongin A for proper gene expression and development. Molecular and cellular biology\| PubMed ID: 15509793	2004
ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex. The Journal of biological chemistry\| PubMed ID: 15590664	2005
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases. Genes & development\| PubMed ID: 15601820	2004
Regulation of heat shock gene expression by RNA polymerase II elongation factor, Elongin A. The Journal of biological chemistry\| PubMed ID: 15611125	2005
The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. The Journal of biological chemistry\| PubMed ID: 15647280	2005
The mammalian Mediator complex. FEBS letters\| PubMed ID: 15680972	2005
The mammalian Mediator complex and its role in transcriptional regulation. Trends in biochemical sciences\| PubMed ID: 15896743	2005
ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16006523	2005
A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex. The Journal of biological chemistry\| PubMed ID: 16230350	2005
In and out: histone variant exchange in chromatin. Trends in biochemical sciences\| PubMed ID: 16257529	2005
Purification of a human SRCAP complex that remodels chromatin by incorporating the histone variant H2A.Z into nucleosomes. Biochemistry\| PubMed ID: 16634648	2006
Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1. Nature cell biology\| PubMed ID: 16906146	2006
Purification and assay of the human INO80 and SRCAP chromatin remodeling complexes. Methods (San Diego, Calif.)\| PubMed ID: 17101442	2006
Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17138671	2006
Identification and Characterization of a Schizosaccharomyces pombe RNA Polymerase II Elongation Factor with Similarity to the Metazoan Transcription Factor ELL. The Journal of biological chemistry\| PubMed ID: 17150956	2007
RNA polymerase II: a "nobel" enzyme demystified. Molecular cell\| PubMed ID: 17157247	2006
YY1 functions with INO80 to activate transcription. Nature structural & molecular biology\| PubMed ID: 17721549	2007
Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1. The Journal of biological chemistry\| PubMed ID: 18077452	2008
Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases. The Journal of biological chemistry\| PubMed ID: 18187417	2008
Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18218781	2008
New clues to actin function in chromatin regulation. Nature structural & molecular biology\| PubMed ID: 18461045	2008
Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. Molecular cell\| PubMed ID: 18922472	2008
Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb1. The EMBO journal\| PubMed ID: 19037258	2008
The INO80 chromatin remodeling complex in transcription, replication and repair. Trends in biochemical sciences\| PubMed ID: 19062292	2009
Mediator comes out from the shadows. Structure (London, England : 1993)\| PubMed ID: 19368880	2009
Direct inhibition of RNA polymerase II transcription by RECQL5. The Journal of biological chemistry\| PubMed ID: 19570979	2009
Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19666485	2009
Proteomics reveals a physical and functional link between hepatocyte nuclear factor 4alpha and transcription factor IID. The Journal of biological chemistry\| PubMed ID: 19805548	2009
Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19920177	2009
Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex. The Journal of biological chemistry\| PubMed ID: 20018852	2010
AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Molecular cell\| PubMed ID: 20159561	2010
O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1. Cell\| PubMed ID: 21295698	2011
Subunit organization of the human INO80 chromatin remodeling complex: an evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. The Journal of biological chemistry\| PubMed ID: 21303910	2011
Function and regulation of the Mediator complex. Current opinion in genetics & development\| PubMed ID: 21330129	2011
Human mediator subunit MED26 functions as a docking site for transcription elongation factors. Cell\| PubMed ID: 21729782	2011
Origins and activity of the Mediator complex. Seminars in cell & developmental biology\| PubMed ID: 21821140	2011
The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters. The EMBO journal\| PubMed ID: 21822215	2011
Endoplasmic reticulum stress-responsive transcription factor ATF6α directs recruitment of the Mediator of RNA polymerase II transcription and multiple histone acetyltransferase complexes. The Journal of biological chemistry\| PubMed ID: 22577136	2012
The human EKC/KEOPS complex is recruited to Cullin2 ubiquitin ligases by the human tumour antigen PRAME. PloS one\| PubMed ID: 22912744	2012
The Mediator complex and transcription elongation. Biochimica et biophysica acta\| PubMed ID: 22983086	2013
Transcriptional elongation factor elongin A regulates retinoic acid-induced gene expression during neuronal differentiation. Cell reports\| PubMed ID: 23122963	2012
Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate. The Journal of biological chemistry\| PubMed ID: 23132853	2012
Immunoaffinity purification of protein complexes from Mammalian cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 23436370	2013
A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction. Nature structural & molecular biology\| PubMed ID: 23563140	2013
Transcriptional properties of mammalian elongin A and its role in stress response. The Journal of biological chemistry\| PubMed ID: 23828199	2013
Role for human mediator subunit MED25 in recruitment of mediator to promoters by endoplasmic reticulum stress-responsive transcription factor ATF6α. The Journal of biological chemistry\| PubMed ID: 23864652	2013
Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes. PLoS genetics\| PubMed ID: 24244196	2013
Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24297934	2013
Subunit architecture and functional modular rearrangements of the transcriptional mediator complex. Cell\| PubMed ID: 24882805	2014